Antiviral and antimicrobial applications of chalcones and their derivatives: From nature to greener synthesis
Chalcones and their derivatives have been widely studied due to their versatile
pharmacological and biological activities, such as anti-inflammatory, antibacterial, antiviral …
pharmacological and biological activities, such as anti-inflammatory, antibacterial, antiviral …
Synthetic non-toxic anti-biofilm agents as a strategy in combating bacterial resistance
RM Hassan, MS Abd El-Maksoud, IAY Ghannam… - European Journal of …, 2023 - Elsevier
The tremendous increase in the bacterial resistance to the available antibiotics is a serious
problem for the treatment of various infections. Biofilm formation in bacteria significantly …
problem for the treatment of various infections. Biofilm formation in bacteria significantly …
1, 2, 3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226
Abstract A new series of 1, 2, 3-triazole-chalcone hybrids has been synthesized and
screened in vitro against a panel of 60 human cancer cell lines according to NCI (USA) …
screened in vitro against a panel of 60 human cancer cell lines according to NCI (USA) …
Synthetic and Semisynthetic Compounds as Antibacterials Targeting Virulence Traits in Resistant Strains: A Narrative Updated Review
This narrative review paper provides an up-to-date overview of the potential of novel
synthetic and semisynthetic compounds as antibacterials that target virulence traits in …
synthetic and semisynthetic compounds as antibacterials that target virulence traits in …
Regulation and controlling the motility properties of Pseudomonas aeruginosa
Chronic infections caused by Pseudomonas aeruginosa have been a major concern as their
spread and mortality continue to be on the rise. These infections are majorly attributed to …
spread and mortality continue to be on the rise. These infections are majorly attributed to …
Design, synthesis, characterization, and anticancer activity of a novel series of O-substituted chalcone derivatives
B Ngameni, K Cedric, AT Mbaveng, M Erdoğan… - Bioorganic & Medicinal …, 2021 - Elsevier
A new series of O-substituted chalcone derivatives bearing an/a allyl-, prenyl-or propargyl-
substituent at different positions of rings A and B and their derivatives as drug leads, was …
substituent at different positions of rings A and B and their derivatives as drug leads, was …
Direct synthesis, characterization, in vitro and in silico studies of simple chalcones as potential antimicrobial and antileishmanial agents
Chalcone represents a vital biosynthetic scaffold owing to its numerous therapeutic effects.
The present study was intended to synthesize 17 chalcone derivatives (3a–q) by direct …
The present study was intended to synthesize 17 chalcone derivatives (3a–q) by direct …
Direct antibacterial and antibiotic resistance modulatory activity of chalcones synthesized from the natural product 2-hydroxy-3, 4, 6-trimethoxyacetophenone
TS Freitas, JC Xavier, RLS Pereira… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic for clinical use lose its effectiveness over time due to bacterial resistance. In this
work, four chalcones with modifications in their ligands were synthesized from the natural …
work, four chalcones with modifications in their ligands were synthesized from the natural …
Chalcones with potential antibacterial and antibiofilm activities against periodontopathogenic bacteria
AAC Satokata, JH Souza, LLO Silva, MB Santiago… - Anaerobe, 2022 - Elsevier
Objectives Periodontitis is a pathology resulting from complex interaction of microorganisms
in the dental biofilm with the host's immune system. Increased use of antibiotics associated …
in the dental biofilm with the host's immune system. Increased use of antibiotics associated …
Quorum quenching activity of pentacyclic triterpenoids leads to inhibition of biofilm formation by Acinetobacter baumannii
The quorum quenching (QQ) potential of three pentacyclic triterpenoids, glycyrrhetinic acid
(GRA), ursolic acid (UA) and betulinic acid (BA), representing distinct groups of compounds …
(GRA), ursolic acid (UA) and betulinic acid (BA), representing distinct groups of compounds …