Ion mobility mass spectrometry of proteins and protein assemblies

C Uetrecht, RJ Rose, E van Duijn, K Lorenzen… - Chemical Society …, 2010 - pubs.rsc.org
Traditionally, mass spectrometry has been a powerful analytical method enabling the
structural analysis of small molecules, and later on peptides and proteins. With the advent of …

Biomolecule analysis by ion mobility spectrometry

BC Bohrer, SI Merenbloom, SL Koeniger… - Annu. Rev. Anal …, 2008 - annualreviews.org
Although nonnative protein conformations, including intermediates along the folding
pathway and kinetically trapped misfolded species that disfavor the native state, are rarely …

Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass …

JC May, CR Goodwin, NM Lareau, KL Leaptrot… - Analytical …, 2014 - ACS Publications
Ion mobility-mass spectrometry measurements which describe the gas-phase scaling of
molecular size and mass are of both fundamental and pragmatic utility. Fundamentally, such …

Fundamentals of traveling wave ion mobility spectrometry

AA Shvartsburg, RD Smith - Analytical chemistry, 2008 - ACS Publications
Traveling wave ion mobility spectrometry (TW IMS) is a new IMS method implemented in the
Synapt IMS/mass spectrometry system (Waters). Despite its wide adoption, the foundations …

[BUCH][B] Differential ion mobility spectrometry: nonlinear ion transport and fundamentals of FAIMS

AA Shvartsburg - 2008 - taylorfrancis.com
Over the last decade, scientific and engineering interests have been shifting from
conventional ion mobility spectrometry (IMS) to field asymmetric waveform ion mobility …

Invited review article: laser vaporization cluster sources

MA Duncan - Review of scientific instruments, 2012 - pubs.aip.org
The laser vaporization cluster source has been used for the production of gas phase atomic
clusters and metal-molecular complexes for 30 years. Numerous experiments in the …

High-sensitivity ion mobility spectrometry/mass spectrometry using electrodynamic ion funnel interfaces

K Tang, AA Shvartsburg, HN Lee, DC Prior… - Analytical …, 2005 - ACS Publications
The utility of ion mobility spectrometry (IMS) for separation of mixtures and structural
characterization of ions has been demonstrated extensively, including in biological and …

Ion mobility spectrometry: a review. Part 1. Structural analysis by mobility measurement

CS Creaser, JR Griffiths, CJ Bramwell, S Noreen… - Analyst, 2004 - pubs.rsc.org
Ion mobility spectrometry (IMS) is an electrophoretic technique that allows ionised analyte
molecules to be separated on the basis of their mobilities in the gas phase. The technique …

[BUCH][B] Structure and properties of atomic nanoclusters

JA Alonso - 2012 - books.google.com
Atomic clusters are aggregates of atoms containing a few to several thousand atoms. Due to
the small size of these pieces of matter, the properties of atomic clusters in general are …

Gas-phase conformations: The ion mobility/ion chromatography method

T Wyttenbach, MT Bowers - Modern Mass Spectrometry, 2003 - Springer
Ion mobility spectrometry coupled to mass spectrometry provides a powerful tool to explore
the three-dimensional shape of polyatomic ions. Applications include the investigation of …