Myeloid-derived suppressor cells (MDSCs) were initially identified in humans and mice with
cancer where they profoundly suppress T cell–and NK cell–mediated antitumor immunity …

Chagas disease is an important neglected disease that affects 6–7 million people
worldwide. The disease has two phases: acute and chronic, in which there are different …

Myeloid‐derived suppressor cells (MDSCs) and tumor‐associated macrophages (TAMs),
two immunosuppressive myeloid components within the tumor microenvironment (TME) …

The production of nitric oxide (NO) is a key defense mechanism against intracellular
pathogens but it must be tightly controlled in order to avoid excessive detrimental oxidative …

Infectious diseases are caused by the invasion of pathogenic microorganisms such as fungi,
bacteria, viruses, and parasites. After infection, disease progression relies on the complex …

Macrophages are the primary immune cells that reside within the myocardium, suggesting
that these mononuclear phagocytes are essential in the orchestration of cardiac immunity …

Chagas disease is a complex tropical pathology caused by the kinetoplastid Trypanosoma
cruzi. This parasite displays massive genetic diversity and has been classified by …

The protozoan Trypanosoma cruzi is the causative agent of Chagas' disease, endemic in
Latin America but present worldwide. Research efforts have focused on the examination of …

Many pathogens, ranging from viruses to multicellular parasites, promote expansion of
MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of …

Lithium (Li) is a relevant mood stabilizer metal for the treatment of bipolar disorder (BD), as it
protects from both depression and mania and reduces the risk of suicide. However, Lihas …