Epithelial ovarian cancer

S Lheureux, C Gourley, I Vergote, AM Oza - The Lancet, 2019 - thelancet.com
Epithelial ovarian cancer generally presents at an advanced stage and is the most common
cause of gynaecological cancer death. Treatment requires expert multidisciplinary care …

[HTML][HTML] Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment

E Schoutrop, L Moyano-Galceran, S Lheureux… - Seminars in cancer …, 2022 - Elsevier
Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

The evolution of ovarian carcinoma subclassification

M Köbel, EY Kang - Cancers, 2022 - mdpi.com
Simple Summary Historically, cancers presenting with their main tumor mass in the ovary
have been classified as ovarian carcinomas (a concise term for epithelial ovarian cancer) …

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma

S Zhang, I Dolgalev, T Zhang, H Ran, DA Levine… - Nature …, 2019 - nature.com
The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial,
with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered …

Molecular characterization of epithelial ovarian cancer: implications for diagnosis and treatment

V Rojas, KM Hirshfield, S Ganesan… - International journal of …, 2016 - mdpi.com
Epithelial ovarian cancer is a highly heterogeneous disease characterized by multiple
histological subtypes. Molecular diversity has been shown to occur within specific …

Ovarian cancer, version 1.2016, NCCN clinical practice guidelines in oncology

RJ Morgan, DK Armstrong, RD Alvarez… - Journal of the National …, 2016 - jnccn.org
This selection from the NCCN Guidelines for Ovarian Cancer focuses on the less common
ovarian histopathologies (LCOHs), because new algorithms were added for LCOHs and …

ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas

KC Wiegand, SP Shah, OM Al-Agha… - … England Journal of …, 2010 - Mass Medical Soc
Background Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis,
but the molecular events involved in this transformation have not been described. Methods …

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

RGW Verhaak, P Tamayo, JY Yang, D Hubbard… - The Journal of clinical …, 2012 - jci.org
Because of the high risk of recurrence in high-grade serous ovarian carcinoma (HGS-OvCa),
the development of outcome predictors could be valuable for patient stratification. Using the …

CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27 Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian …

JS Nielsen, RA Sahota, K Milne, SE Kost… - Clinical cancer …, 2012 - aacrjournals.org
Purpose: Tumor-infiltrating lymphocytes (TIL), in particular CD8+ T cells and CD20+ B cells,
are strongly associated with survival in ovarian cancer and other carcinomas. Although …

Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis

WG McCluggage - Pathology-Journal of the RCPA, 2011 - journals.lww.com
Ovarian carcinomas comprise a heterogeneous group of neoplasms, the four most common
subtypes being serous, endometrioid, clear cell and mucinous. In recent years, our …