The neural basis of psychedelic action
Psychedelics are serotonin 2A receptor agonists that can lead to profound changes in
perception, cognition and mood. In this review, we focus on the basic neurobiology …
perception, cognition and mood. In this review, we focus on the basic neurobiology …
Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders
Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …
warrants a better understanding of the neurobiological mechanisms underlying the effects of …
Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder
Psilocybin has shown promise for the treatment of mood disorders, which are often
accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have …
accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have …
[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …
REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics
This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …
Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential
Serotonergic psychedelics possess considerable therapeutic potential. Although 5-HT2A
receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5 …
receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5 …
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies
Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
Default mode network modulation by psychedelics: a systematic review
Psychedelics are a unique class of drug that commonly produce vivid hallucinations as well
as profound psychological and mystical experiences. A grou** of interconnected brain …
as profound psychological and mystical experiences. A grou** of interconnected brain …
Cellular mechanisms of conscious processing
Recent breakthroughs in neurobiology indicate that the time is ripe to understand how
cellular-level mechanisms are related to conscious experience. Here, we highlight the …
cellular-level mechanisms are related to conscious experience. Here, we highlight the …
Models of psychedelic drug action: modulation of cortical-subcortical circuits
Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …
recaptured the imagination of both science and popular culture, and may have efficacy in …