The gut microbiome: Relationships with disease and opportunities for therapy
Over the past decade, our view of human-associated microbes has expanded beyond that of
a few species toward an appreciation of the diverse and niche-specialized microbial …
a few species toward an appreciation of the diverse and niche-specialized microbial …
The gut microbiota in the first decade of life
Appreciation of the importance of the gut microbiome is growing, and it is becoming
increasingly relevant to identify preventive or therapeutic solutions targeting it. The …
increasingly relevant to identify preventive or therapeutic solutions targeting it. The …
[HTML][HTML] Developmental trajectory of the healthy human gut microbiota during the first 5 years of life
The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is
established at birth. However, the succession by which different bacteria are incorporated …
established at birth. However, the succession by which different bacteria are incorporated …
Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches
RB Sartor, GD Wu - Gastroenterology, 2017 - Elsevier
Intestinal microbiota are involved in the pathogenesis of Crohn's disease, ulcerative colitis,
and pouchitis. We review the mechanisms by which these gut bacteria, fungi, and viruses …
and pouchitis. We review the mechanisms by which these gut bacteria, fungi, and viruses …
Regulation of inflammation by microbiota interactions with the host
The study of the intestinal microbiota has begun to shift from cataloging individual members
of the commensal community to understanding their contributions to the physiology of the …
of the commensal community to understanding their contributions to the physiology of the …
A causal mechanism for childhood acute lymphoblastic leukaemia
M Greaves - Nature Reviews Cancer, 2018 - nature.com
In this Review, I present evidence supporting a multifactorial causation of childhood acute
lymphoblastic leukaemia (ALL), a major subtype of paediatric cancer. ALL evolves in two …
lymphoblastic leukaemia (ALL), a major subtype of paediatric cancer. ALL evolves in two …
Personalized map** of drug metabolism by the human gut microbiome
The human gut microbiome harbors hundreds of bacterial species with diverse biochemical
capabilities. Dozens of drugs have been shown to be metabolized by single isolates from …
capabilities. Dozens of drugs have been shown to be metabolized by single isolates from …
Healthy infants harbor intestinal bacteria that protect against food allergy
There has been a striking generational increase in life-threatening food allergies in
Westernized societies,. One hypothesis to explain this rising prevalence is that twenty-first …
Westernized societies,. One hypothesis to explain this rising prevalence is that twenty-first …
Infant gut microbiome associated with cognitive development
Background Studies in rodents provide compelling evidence that microorganisms inhabiting
the gut influence neurodevelopment. In particular, experimental manipulations that alter …
the gut influence neurodevelopment. In particular, experimental manipulations that alter …
Effects of microbiota-directed foods in gnotobiotic animals and undernourished children
INTRODUCTION There is a dimension to postnatal human development that involves
assembly of microbial communities in different body habitats, including the gut. Children with …
assembly of microbial communities in different body habitats, including the gut. Children with …