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Mechanical state transitions in the regulation of tissue form and function
From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
Adherens junctions as molecular regulators of emergent tissue mechanics
Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …
coordinated action of many cells. Recent studies have revealed that tissue material …
E-cadherin tunes tissue mechanical behavior before and during morphogenetic tissue flows
Adhesion between epithelial cells enables the remarkable mechanical behavior of epithelial
tissues during morphogenesis. However, it remains unclear how cell-cell adhesion …
tissues during morphogenesis. However, it remains unclear how cell-cell adhesion …
Polarity-driven three-dimensional spontaneous rotation of a cell doublet
Mechanical interactions between cells play a fundamental role in the self-organization of
organisms. How these interactions drive coordinated cell movement in three dimensions …
organisms. How these interactions drive coordinated cell movement in three dimensions …
Influencing inter-cellular junctions with nanomaterials
J Wang, G Zhang, K ** Drosophila Germband Epithelium
Epithelial cells generate functional tissues in develo** embryos through collective
movements and shape changes. In some morphogenetic events, a tissue dramatically …
movements and shape changes. In some morphogenetic events, a tissue dramatically …
Evo-Devo Mechanobiology: The Missing Link
While the modern framework of evolutionary development (evo-devo) has been decidedly
genetic, historic analyses have also considered the importance of mechanics in the …
genetic, historic analyses have also considered the importance of mechanics in the …
An emerging role for tissue plasticity in developmental precision
SR Naganathan - Biochemical Society Transactions, 2024 - portlandpress.com
Reproducible tissue morphology is a fundamental feature of embryonic development. To
ensure such robustness during tissue morphogenesis, inherent noise in biological …
ensure such robustness during tissue morphogenesis, inherent noise in biological …
Generic theory of interacting, spinning, active polar particles: A model for cell aggregates
We present a generic framework for describing interacting, spinning, active polar particles,
aimed at modeling dense cell aggregates, where cells are treated as polar, rotating objects …
aimed at modeling dense cell aggregates, where cells are treated as polar, rotating objects …