Synthetic organic chemistry has developed in a fascinating way over the past decades.
Several highly selective procedures have been developed which allow the preparation of …

Natural and synthetic cyclopropanes bearing simple functionalities are endowed with a
large spectrum of biological properties ranging from enzyme inhibitions to insecticidal …

A new, interdisciplinary research area has emerged known as bioorganometallic chemistry.
It focuses on the introduction of organometallic fragments into biomolecules (see, for …

Peptide and protein biological activities depend on their three dimensionals structures in the
free state and when interacting with their receptors/acceptors. The backbone conformations …

None of the naturally occurring amino acids containing a cyclopropyl group is proteinogenic,
but most of them bring about some interesting and important biological activity. This also …

Alkylation of stabilized carbanions is the most fundamental carbon±carbon bond-forming
reaction in organic chemistry. 1 Recent NMR and X-ray analyses, stimulated by the central …

Conformationally constrained amino acids (AAs) have been the focus of both synthetic and
medicinal chemistry, particularly as they apply to the design of novel peptides. 1 Rigidified …

Metal‐catalyzed allylic alkylation reactions between dual nucleophiles and dual
electrophiles represent a powerful set of methods for the synthesis of small‐, medium‐, and …

Ogawa et al., CA113: 111406, 1990.* Gaucher, Et Al:“Palladium (0) Catalyzed Tandem
Alkyla tion and SN'Cyclization of 1, 4-Dichlorobut-2-ene by the N-(Diphenylmethylene) …

The catalytic enantioselective reaction of diphenylmethylidene‐protected α‐
aminoacetonitriles with imines has been developed. Good yields and diastereo‐and …