New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Lung cancer screening, version 3.2018, NCCN clinical practice guidelines in oncology

DE Wood, EA Kazerooni, SL Baum, GA Eapen… - Journal of the National …, 2018 - jnccn.org
Lung cancer is the leading cause of cancer-related mortality in the United States and
worldwide. Early detection of lung cancer is an important opportunity for decreasing …

Inferring gene expression from cell-free DNA fragmentation profiles

MS Esfahani, EG Hamilton, M Mehrmohamadi… - Nature …, 2022 - nature.com
Profiling of circulating tumor DNA (ctDNA) in the bloodstream shows promise for
noninvasive cancer detection. Chromatin fragmentation features have previously been …

End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography

D Ardila, AP Kiraly, S Bharadwaj, B Choi, JJ Reicher… - Nature medicine, 2019 - nature.com
With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer
death in the United States. Lung cancer screening using low-dose computed tomography …

Complication rates of CT-guided transthoracic lung biopsy: meta-analysis

WJ Heerink, GH de Bock, GJ de Jonge, HJM Groen… - European …, 2017 - Springer
Objectives To meta-analyze complication rate in computed tomography (CT)-guided
transthoracic lung biopsy and associated risk factors. Methods Four databases were …

[HTML][HTML] British Thoracic Society guidelines for the investigation and management of pulmonary nodules: accredited by NICE

MEJ Callister, DR Baldwin, AR Akram, S Barnard… - Thorax, 2015 - thorax.bmj.com
This guideline is based on a comprehensive review of the literature on pulmonary nodules
and expert opinion. Although the management pathway for the majority of nodules detected …

Evaluation of individuals with pulmonary nodules: When is it lung cancer?: Diagnosis and management of lung cancer: American College of Chest Physicians …

MK Gould, J Donington, WR Lynch, PJ Mazzone… - Chest, 2013 - Elsevier
Objectives The objective of this article is to update previous evidence-based
recommendations for evaluation and management of individuals with solid pulmonary …

Screening tests: a review with examples

LD Maxim, R Niebo, MJ Utell - Inhalation toxicology, 2014 - Taylor & Francis
Screening tests are widely used in medicine to assess the likelihood that members of a
defined population have a particular disease. This article presents an overview of such tests …

Establishing the diagnosis of lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice …

MP Rivera, AC Mehta, MM Wahidi - Chest, 2013 - Elsevier
Background Lung cancer is usually suspected in individuals who have an abnormal chest
radiograph or have symptoms caused by either local or systemic effects of the tumor. The …

Screening for lung cancer: CHEST guideline and expert panel report

PJ Mazzone, GA Silvestri, S Patel, JP Kanne… - Chest, 2018 - Elsevier
Background Low-dose chest CT screening for lung cancer has become a standard of care in
the United States in the past few years, in large part due to the results of the National Lung …