Gut microbiome: decision-makers in the microenvironment of colorectal cancer

J Han, B Zhang, Y Zhang, T Yin, Y Cui, J Liu… - Frontiers in Cellular …, 2023 - frontiersin.org
Colorectal cancer (CRC) is a common malignancy of the gastrointestinal tract, accounting for
the second most common cause of gastrointestinal tumors. As one of the intestinal barriers …

Sex differences in colorectal cancer: with a focus on sex hormone–gut microbiome axis

Z Wu, Y Huang, R Zhang, C Zheng, F You… - Cell Communication and …, 2024 - Springer
Sexual dimorphism has been observed in the incidence and prognosis of colorectal cancer
(CRC), with men generally exhibiting a slightly higher incidence than women. Research …

NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1

JH Cao, CH Cao, JL Lin, SY Li, LJ He, K Han, JW Chen… - Cell Reports, 2024 - cell.com
Deficiency of DNA repair pathways drives the development of colorectal cancer. However,
the role of the base excision repair (BER) pathway in colorectal cancer initiation remains …

Long-term trends in the burden of colorectal cancer in Europe over three decades: a joinpoint regression and age-period-cohort analysis

D Long, C Mao, Z Zhang, Y Liu, J Li, Y Xu… - Frontiers in …, 2023 - frontiersin.org
Background The burden of colorectal cancer (CRC) in Europe is at a high level, but the
epidemiological features have not yet been systematically studied. This study aimed to …

MetOrigin 2.0: Advancing the discovery of microbial metabolites and their origins

G Yu, C Xu, X Wang, F Ju, J Fu, Y Ni - Imeta, 2024 - Wiley Online Library
First introduced in 2021, MetOrigin has quickly established itself as a powerful web server to
distinguish microbial metabolites and identify the bacteria responsible for specific metabolic …

Apple polysaccharide improves age-matched cognitive impairment and intestinal aging through microbiota-gut-brain axis

W Zhang, Y Zhong, Z Wang, F Tang, C Zheng - Scientific Reports, 2024 - nature.com
The Apple polysaccharides (AP), extracted from the fruit of apple, has been used to treat
multiple pathological diseases. In this study, we evaluated the effects of AP on cognitive …

[HTML][HTML] Gut microbiome and metabolites mediate the benefits of caloric restriction in mice after acute kidney injury

XX Zhu, X Fu, XY Meng, JB Su, GL Zheng, AJ Xu… - Redox Biology, 2024 - Elsevier
The role of gut microbiome in acute kidney injury (AKI) is increasing recognized. Caloric
restriction (CR) has been shown to enhance the resistance to ischemia/reperfusion injury to …

Third-generation PacBio sequencing to explore gut bacteria and gender in colorectal cancer

S Yu, J Chu, Y Wu, J Zhuang, Z Qu, Y Song, X Wu… - Microbial …, 2024 - Elsevier
Background Gut bacteria have an important influence on colorectal cancer (CRC). The
differences of gut bacteria between genders have been the hot spots. Objective To analyze …

Intestinal Akkermansia muciniphila is Beneficial to Functional Recovery Following Ischemic Stroke

K Li, W Ding, X Li, H Gao, S Wang, T Li, H Zhao… - Journal of Neuroimmune …, 2024 - Springer
Recent studies have demonstrated the interaction between gut microbiota and brain on
ischemic stroke, but the roles of gut microbiota in the pathophysiology of ischemic stroke …

[HTML][HTML] Genetically predicted causal effects of gut microbiota and gut metabolites on digestive tract Cancer: a two-sample Mendelian randomization analysis

XJ Li, MG Gao, XX Chen, YM Rong… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Background Evidence from numerous observational studies and clinical trials has linked gut
microbiota and metabolites to digestive tract cancer. However, the causal effect between …