Electrophysiologic basis for the antiarrhythmic actions of ranolazine
C Antzelevitch, A Burashnikov, S Sicouri, L Belardinelli - Heart rhythm, 2011 - Elsevier
Ranolazine is a Food and Drug Administration–approved antianginal agent. Experimental
and clinical studies have shown that ranolazine has antiarrhythmic effects in both ventricles …
and clinical studies have shown that ranolazine has antiarrhythmic effects in both ventricles …
Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics
N Chiamvimonvat, Y Chen‐Izu… - The Journal of …, 2017 - Wiley Online Library
This is the second of the two White Papers from the fourth UC Davis Cardiovascular
Symposium Systems Approach to Understanding Cardiac Excitation–Contraction Coupling …
Symposium Systems Approach to Understanding Cardiac Excitation–Contraction Coupling …
A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms
JD Moreno, ZI Zhu, PC Yang, JR Bankston… - Science translational …, 2011 - science.org
A long-sought, and thus far elusive, goal has been to develop drugs to manage diseases of
excitability. One such disease that affects millions each year is cardiac arrhythmia, which …
excitability. One such disease that affects millions each year is cardiac arrhythmia, which …
Injectable Drug‐Releasing Microporous Annealed Particle Scaffolds for Treating Myocardial Infarction
Intramyocardial injection of hydrogels offers great potential for treating myocardial infarction
(MI) in a minimally invasive manner. However, traditional bulk hydrogels generally lack …
(MI) in a minimally invasive manner. However, traditional bulk hydrogels generally lack …
Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation
A Burashnikov, S Sicouri, JM Di Diego… - Journal of the American …, 2010 - jacc.org
Objectives: The aim of this study was to evaluate the effectiveness of a combination of
dronedarone and ranolazine in suppression of atrial fibrillation (AF). Background: Safe and …
dronedarone and ranolazine in suppression of atrial fibrillation (AF). Background: Safe and …
Atrial fibrillation as a prognostic indicator in medium to large‐sized dogs with myxomatous mitral valvular degeneration and congestive heart failure
SW Jung, W Sun, LG Griffiths… - Journal of veterinary …, 2016 - Wiley Online Library
Background The prevalence and prognostic importance of atrial fibrillation (AF) on survival
in nonsmall breed dogs with myxomatous mitral valvular disease (MMVD) and congestive …
in nonsmall breed dogs with myxomatous mitral valvular disease (MMVD) and congestive …
Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels
Cardiac sodium channels are established therapeutic targets for the management of
inherited and acquired arrhythmias by class I anti-arrhythmic drugs (AADs). These drugs …
inherited and acquired arrhythmias by class I anti-arrhythmic drugs (AADs). These drugs …
TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes
SH Limberg, MF Netter, C Rolfes, S Rinné… - Cellular Physiology and …, 2011 - karger.com
Abstract Background/Aims: Atrial fibrillation is the most common arrhythmia in the elderly,
and potassium channels with atrium-specific expression have been discussed as targets to …
and potassium channels with atrium-specific expression have been discussed as targets to …
Atrial-selective inhibition of sodium-channel current by Wenxin Keli is effective in suppressing atrial fibrillation
A Burashnikov, A Petroski, D Hu, H Barajas-Martinez… - Heart rhythm, 2012 - Elsevier
BACKGROUND: Wenxin Keli is a Chinese herb extract reported to be of benefit in the
treatment of cardiac arrhythmias, cardiac inflammation, and heart failure. METHODS AND …
treatment of cardiac arrhythmias, cardiac inflammation, and heart failure. METHODS AND …
Systematic review and meta-analysis of the efficacy of cardioversion by vernakalant and comparators in patients with atrial fibrillation
LD Bash, JL Buono, GM Davies, A Martin… - … drugs and therapy, 2012 - Springer
Purpose Rate and rhythm control are two well established treatment objectives for atrial
fibrillation (AF) patients. While symptom reduction is a primary treatment goal, therapeutic …
fibrillation (AF) patients. While symptom reduction is a primary treatment goal, therapeutic …