Liposomes and extracellular vesicles as drug delivery systems: a comparison of composition, pharmacokinetics, and functionalization

L van der Koog, TB Gandek… - Advanced healthcare …, 2022 - Wiley Online Library
Over the past decades, lipid‐based nanoparticle drug delivery systems (DDS) have caught
the attention of researchers worldwide, encouraging the field to rapidly develop improved …

Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …

S Kansız, YM Elçin - Advances in Colloid and Interface Science, 2023 - Elsevier
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …

Synthetic biology: bottom-up assembly of molecular systems

S Hirschi, TR Ward, WP Meier, DJ Müller… - Chemical …, 2022 - ACS Publications
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …

[HTML][HTML] Skin drug delivery using lipid vesicles: A starting guideline for their development

AJ Guillot, M Martínez-Navarrete, TM Garrigues… - Journal of Controlled …, 2023 - Elsevier
Lipid vesicles can provide a cost-effective enhancement of skin drug absorption when
vesicle production process is optimised. It is an important challenge to design the ideal …

Influence of cholesterol on liposome stability and on in vitro drug release

ML Briuglia, C Rotella, A McFarlane… - Drug delivery and …, 2015 - Springer
Cholesterol plays a strategic role in liposome composition; however, the quantity used to
achieve an appropriate formulation has not been yet clarified. Therefore, by screening …

Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake.

J Sun, L Zhang, J Wang, Q Feng, D Liu… - … (deerfield beach, fla.), 2014 - europepmc.org
Core-shell nanoparticles (NPs) with lipid shells and varying water content and rigidity but
with the same chemical composition, size, and surface properties are assembled using a …

A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles

JP Straehla, C Hajal, HC Safford, GS Offeddu… - Proceedings of the …, 2022 - pnas.org
The blood–brain barrier represents a significant challenge for the treatment of high-grade
gliomas, and our understanding of drug transport across this critical biointerface remains …

Force measurements with the atomic force microscope: Technique, interpretation and applications

HJ Butt, B Cappella, M Kappl - Surface science reports, 2005 - Elsevier
The atomic force microscope (AFM) is not only a tool to image the topography of solid
surfaces at high resolution. It can also be used to measure force-versus-distance curves …

Effect of nanoparticle composition, size, shape, and stiffness on penetration across the blood–brain barrier

TD Brown, N Habibi, D Wu, J Lahann… - … biomaterials science & …, 2020 - ACS Publications
The delivery of therapeutics to the brain in an efficient, noninvasive manner continues to be
a major unmet need in the field of drug delivery. One significant impediment to brain delivery …

Morphology and microstructural analysis of bioactive-loaded micro/nanocarriers via microscopy techniques; CLSM/SEM/TEM/AFM

SR Falsafi, H Rostamabadi, E Assadpour… - Advances in Colloid and …, 2020 - Elsevier
Efficient characterization of the physicochemical attributes of bioactive-loaded micro/nano-
vehicles is crucial for the successful product development. The introduction of outstanding …