Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Abstract Background Garlic (Allium sativum L.) is a common herb consumed worldwide as
functional food and traditional remedy for the prevention of infectious diseases since ancient …
functional food and traditional remedy for the prevention of infectious diseases since ancient …
Natural products as sources of new drugs from 1981 to 2014
DJ Newman, GM Cragg - Journal of natural products, 2016 - ACS Publications
This contribution is a completely updated and expanded version of the four prior analogous
reviews that were published in this journal in 1997, 2003, 2007, and 2012. In the case of all …
reviews that were published in this journal in 1997, 2003, 2007, and 2012. In the case of all …
[HTML][HTML] TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
SARS-CoV-2 is associated with broad tissue tropism, a characteristic often determined by
the availability of entry receptors on host cells. Here, we show that TMEM106B, a lysosomal …
the availability of entry receptors on host cells. Here, we show that TMEM106B, a lysosomal …
[PDF][PDF] Identification of potent COVID-19 main protease (Mpro) inhibitors from natural polyphenols: an in silico strategy unveils a hope against CORONA
COVID-19, a rapidly spreading new strain of coronavirus, has affected more than 150
countries and received worldwide attention. The lack of efficacious drugs or vaccines …
countries and received worldwide attention. The lack of efficacious drugs or vaccines …
In silico identification of potential inhibitors from Cinnamon against main protease and spike glycoprotein of SARS CoV-2
Cinnamon has been utilized to remedy a lot of afflictions of humans. Literary works illustrate
that it possesses numerous biological activities. Our research study is intended to recognize …
that it possesses numerous biological activities. Our research study is intended to recognize …
Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses
Y Ma, E Frutos-Beltrán, D Kang… - Chemical Society …, 2021 - pubs.rsc.org
During the last forty years we have witnessed impressive advances in the field of antiviral
drug discovery culminating with the introduction of therapies able to stop human …
drug discovery culminating with the introduction of therapies able to stop human …
Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond
Infections with flaviviruses, such as dengue, West Nile virus and the recently re-emerging
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …
Potential antiviral action of alkaloids
Viral infections and outbreaks have become a major concern and are one of the main
causes of morbidity and mortality worldwide. The development of successful antiviral …
causes of morbidity and mortality worldwide. The development of successful antiviral …
Antiviral strategies targeting host factors and mechanisms obliging+ ssRNA viral pathogens
The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …
emergence of challenging variants has created an urgent need of alternative therapeutic …
Antiviral properties of the natural polyphenols delphinidin and epigallocatechin gallate against the flaviviruses West Nile virus, Zika virus, and dengue virus
Á Vázquez-Calvo, N Jiménez de Oya… - Frontiers in …, 2017 - frontiersin.org
The Flavivirus genus contains important pathogens, such as West Nile virus (WNV), Zika
virus (ZIKV), and Dengue virus (DENV), which are enveloped plus-strand RNA viruses …
virus (ZIKV), and Dengue virus (DENV), which are enveloped plus-strand RNA viruses …