Publisher Summary The development and progression of cancer is associated with the
alterations of genes that control growth and differentiation. The accumulation of genetic …

Uterine leiomyoma—a benign smooth muscle tumor—has recently been found to contain
tumor‐specific chromosome aberrations. Although only normal karyotypes were detected in …

Background Mosaic loss of Y chromosome (LOY) is the most common chromosomal
alteration in aging men. Here, we use single-cell RNA and ATAC sequencing to show that …

Cancer of the bladder is the fifth most common type of cancer in the United States, with an
annual incidence of approximately 18 cases per 100,000 or more than 50,000 new cases …

We report on the cytogenetic analyses of 158 cases of metastatic malignant melanoma,
comprised of 63 cases with regional disease (RD) and 95 cases with distant (metastatic) …

BACKGROUND: The specificity of brush cytology for detection of malignant pancreatobiliary
strictures is high, but its sensitivity is moderate. Fluorescence in situ hybridization (FISH) can …

Defective hematopoiesis supporting capacity of bone marrow (BM) stroma has been
implicated in the pathophysiology of myelodysplastic syndromes (MDS). The aim of this …

To examine the significance of Y chromosome losses in bladder cancer, fluorescence in situ
hybridization (FISH) was used to determine its prevalence and associations with known …

Chromosome analysis of solid tumors is becoming an increasingly useful tool to help
establish a correct diagnosis and to provide prognostically important information …

A review of chromosomal analyses of human lung carcinomas is presented. Karyotypic
studies have revealed multiple cytogenetic changes in most small cell lung carcinomas …