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Glucagon-like peptide-1 receptor: mechanisms and advances in therapy
Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital
component of the G protein-coupled receptor (GPCR) family and is found primarily on the …
component of the G protein-coupled receptor (GPCR) family and is found primarily on the …
GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances
Currently, the clinical treatment of critical bone defects attributed to various causes remains
a great challenge, and repairing these defects with synthetic bone substitutes is the most …
a great challenge, and repairing these defects with synthetic bone substitutes is the most …
Engineered MgO nanoparticles for cartilage-bone synergistic therapy
The emerging therapeutic strategies for osteoarthritis (OA) are shifting toward
comprehensive approaches that target periarticular tissues, involving both cartilage and …
comprehensive approaches that target periarticular tissues, involving both cartilage and …
[HTML][HTML] Review on magnesium and magnesium-based alloys as biomaterials for bone immobilization
M He, L Chen, M Yin, S Xu, Z Liang - Journal of Materials Research and …, 2023 - Elsevier
Magnesium alloy has become one of the third-generation biomedical materials to promote
bone tissue regeneration. Compared to other metal implants, magnesium metal is …
bone tissue regeneration. Compared to other metal implants, magnesium metal is …
[HTML][HTML] Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds
G Zhu, T Zhang, M Chen, K Yao, X Huang, B Zhang… - Bioactive materials, 2021 - Elsevier
Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …
approaches, autologous and allogeneic bone grafting have not achieved the ideal …
Scaffolds for bone-tissue engineering
Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …
[HTML][HTML] Magnesium-based biomaterials as emerging agents for bone repair and regeneration: From mechanism to application
H Zhou, B Liang, H Jiang, Z Deng, K Yu - Journal of Magnesium and Alloys, 2021 - Elsevier
Magnesium (Mg) is the fourth most abundant element in the human body and is important in
terms of specific osteogenesis functions. Here, we provide a comprehensive review of the …
terms of specific osteogenesis functions. Here, we provide a comprehensive review of the …
Biodegradable magnesium‐based implants in orthopedics—a general review and perspectives
Biodegradable Mg‐based metals may be promising orthopedic implants for treating
challenging bone diseases, attributed to their desirable mechanical and osteopromotive …
challenging bone diseases, attributed to their desirable mechanical and osteopromotive …
Alloying design of biodegradable zinc as promising bone implants for load-bearing applications
Magnesium-based biodegradable metals (BMs) as bone implants have better mechanical
properties than biodegradable polymers, yet their strength is roughly less than 350 MPa. In …
properties than biodegradable polymers, yet their strength is roughly less than 350 MPa. In …
Design of biodegradable, implantable devices towards clinical translation
Biodegradable materials, including natural and synthetic polymers and hydrolyzable metals,
constitute the main components of temporary, implantable medical devices. Besides the …
constitute the main components of temporary, implantable medical devices. Besides the …