Autophagy and cancer drug resistance in dialogue: pre-clinical and clinical evidence
The emergence of drug resistance is a major challenge for oncologists. Resistance can be
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
An update on the molecular biology of glioblastoma, with clinical implications and progress in its treatment
Glioblastoma multiforme (GBM) is the most aggressive and common malignant primary brain
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …
[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …
suppression. Poor bioavailability of anticancer compounds and the presence of biological …
Molecular landscape of LncRNAs in prostate cancer: a focus on pathways and therapeutic targets for intervention
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
The long and short non-coding RNAs modulating EZH2 signaling in cancer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …
encoding proteins. However, they participate in developmental and biological processes …
[HTML][HTML] A bioinformatics analysis, pre-clinical and clinical conception of autophagy in pancreatic cancer: complexity and simplicity in crosstalk
Pancreatic cancer (PC) is a serious gastrointestinal tract disease for which the 5-year
survival rate is less than 10%, even in developed countries such as the USA. The genomic …
survival rate is less than 10%, even in developed countries such as the USA. The genomic …
Biomedical application of metal-organic frameworks (MOFs) in cancer therapy: stimuli-responsive and biomimetic nanocomposites in targeted delivery, phototherapy …
The nanotechnology is an interdisciplinary field that has become a hot topic in cancer
therapy. Metal-organic frameworks (MOFs) are porous materials and hybrid composites …
therapy. Metal-organic frameworks (MOFs) are porous materials and hybrid composites …
Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
Synchronous disintegration of ferroptosis defense axis via engineered exosome‐conjugated magnetic nanoparticles for glioblastoma therapy
B Li, X Chen, W Qiu, R Zhao, J Duan… - Advanced …, 2022 - Wiley Online Library
Glioblastoma (GBM) is one of the most fatal central nervous system tumors and lacks
effective or sufficient therapies. Ferroptosis is a newly discovered method of programmed …
effective or sufficient therapies. Ferroptosis is a newly discovered method of programmed …
NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition
Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …