The Fasciclin 1 (FAS1) domain is an ancient structural motif in extracellular proteins present
in all kingdoms of life and particularly abundant in plants. The FAS1 domain accommodates …

Transforming growth factor-β-induced protein (TGFBIp), an extracellular matrix protein, is the
second most abundant protein in the corneal stroma. In this review, we summarize the …

Background: Scavenger receptors Stabilin-1 (Stab1) and Stabilin-2 (Stab2) are preferentially
expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating …

Approximately 10% of fractures will not heal without intervention. Current treatments can be
marginally effective, costly, and some have adverse effects. A safe and manufacturable …

This study analyzed the transcriptional changes in primary human corneal stromal
fibroblasts (hCSFs) grown under quiescent (serum-free) and proliferating (serum …

Background Chronic non-atrophic gastritis (CNG) is the most common type of chronic
gastritis. If not actively treated, it may induce gastric cancer (GC). Western medicine is …

Dickkopf‐related protein (DKK) 3, a member of the DKK family, is a secreted glycoprotein
that acts as a modulator of Wnt signaling in organogenesis and carcinogenesis. Recent …

Background Keratoconus (KC) is the most common ectatic corneal disease, characterized
by significantly localized thinning of the corneal stroma. Genetic, environmental, hormonal …

Introduction Transforming growth factor beta induced (TGFBI) gene mutations have been
reported as the cause of a group of genetically inherited, visually debilitating, corneal …

The ocular surface, comprised of the corneal and conjunctival epithelium, innervation
system, immune components, and tear-film apparatus, plays a key role in ocular integrity as …