A Paradigm Shift in Catalysis: Electro-and Photomediated Nickel-Catalyzed Cross-Coupling Reactions

MD Palkowitz, MA Emmanuel… - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Transition-metal catalyzed cross-coupling reactions are fundamental reactions
in organic chemistry, facilitating strategic bond formations for accessing natural products …

Simplifying Access to Targeted Protein Degraders via Nickel Electrocatalytic Cross‐Coupling

P Neigenfind, L Massaro, Á Péter… - Angewandte Chemie …, 2024 - Wiley Online Library
C− C linked glutarimide‐containing structures with direct utility in the preparation of cereblon‐
based degraders (PROTACs, CELMoDs) can be assessed in a single step from …

Electrochemical Synthesis of Unnatural Amino Acids Embedding 5-and 6-Membered Heteroaromatics

E Bombonato, V Fasano, D Pecorari, L Fornasari… - ACS …, 2024 - ACS Publications
Using a commercially available potentiostat, the electrochemical synthesis of unnatural
amino acids bearing heteroaromatics on the lateral chain has been accomplished. This …

General, Direct Ni-Catalyzed Cross-Coupling of Tertiary Synthons with Heteroaryl Halides

P Richardson - Synfacts, 2023 - thieme-connect.com
Decarboxylative coupling represents an attractive method for the cross-coupling of alkyl
fragments with heteroaryl halides, though while a broad scope of primary/secondary acids …