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Physiology and inflammation driven pathophysiology of iron homeostasis—mechanistic insights into anemia of inflammation and its treatment
Anemia is very common in patients with inflammatory disorders. Its prevalence is associated
with severity of the underlying disease, and it negatively affects quality of life and cardio …
with severity of the underlying disease, and it negatively affects quality of life and cardio …
Renal association clinical practice guideline on Anaemia of Chronic Kidney Disease
A Mikhail, C Brown, JA Williams, V Mathrani… - BMC nephrology, 2017 - Springer
Anaemia is a commonly diagnosed complication among patients suffering with chronic
kidney disease. If left untreated, it may affect patient quality of life. There are several causes …
kidney disease. If left untreated, it may affect patient quality of life. There are several causes …
[HTML][HTML] Impact of inflammation on ferritin, hepcidin and the management of iron deficiency anemia in chronic kidney disease
N Ueda, K Takasawa - Nutrients, 2018 - mdpi.com
Iron deficiency anemia (IDA) is a major problem in chronic kidney disease (CKD), causing
increased mortality. Ferritin stores iron, representing iron status. Hepcidin binds to …
increased mortality. Ferritin stores iron, representing iron status. Hepcidin binds to …
Kidney Disease: Improving Global Outcomes guidelines on anaemia management in chronic kidney disease: a European Renal Best Practice position statement
Abstract Recently, the Kidney Disease: Improving Global Outcomes (KDIGO) group has
produced comprehensive clinical practice guidelines for the management of anaemia in …
produced comprehensive clinical practice guidelines for the management of anaemia in …
FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease
R Evstatiev, P Marteau, T Iqbal, IL Khalif, J Stein… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Iron deficiency anemia (IDA) is common in chronic diseases and
intravenous iron is an effective and recommended treatment. However, dose calculations …
intravenous iron is an effective and recommended treatment. However, dose calculations …
Physiology and pharmacology of erythropoietin
Human erythropoietin (Epo) is a 30.4 kDa glycoprotein hormone composed of a single 165
amino acid residues chain to which four glycans are attached. The kidneys are the primary …
amino acid residues chain to which four glycans are attached. The kidneys are the primary …
The impact of CKD anaemia on patients: incidence, risk factors, and clinical outcomes—a systematic literature review
E Palaka, S Grandy, H van Haalen… - International journal …, 2020 - Wiley Online Library
Anaemia is a common consequence of chronic kidney disease (CKD); however, the risk
factors for its development and its impact on outcomes have not been well synthesised …
factors for its development and its impact on outcomes have not been well synthesised …
Erythropoietic response and outcomes in kidney disease and type 2 diabetes
Background Non–placebo-controlled trials of erythropoiesis-stimulating agents (ESAs)
comparing lower and higher hemoglobin targets in patients with chronic kidney disease …
comparing lower and higher hemoglobin targets in patients with chronic kidney disease …
Current misconceptions in diagnosis and management of iron deficiency
The prevention and treatment of iron deficiency is a major public health goal. Challenges in
the treatment of iron deficiency include finding and addressing the underlying cause and the …
the treatment of iron deficiency include finding and addressing the underlying cause and the …
Very‐short‐term perioperative intravenous iron administration and postoperative outcome in major orthopedic surgery: a pooled analysis of observational data from …
M Muñoz, S Gómez‐Ramírez, J Cuenca… - …, 2014 - Wiley Online Library
Background Postoperative nosocomial infection (PNI) is a severe complication in surgical
patients. Known risk factors of PNI such as allogeneic blood transfusions (ABTs), anemia …
patients. Known risk factors of PNI such as allogeneic blood transfusions (ABTs), anemia …