Immune responses to retinal gene therapy using adeno-associated viral vectors–Implications for treatment success and safety
K Bucher, E Rodríguez-Bocanegra… - Progress in retinal and …, 2021 - Elsevier
Recombinant adeno-associated virus (AAV) is the leading vector for gene therapy in the
retina. As non-pathogenic, non-integrating, replication deficient vector, the recombinant virus …
retina. As non-pathogenic, non-integrating, replication deficient vector, the recombinant virus …
The Baltimore classification of viruses 50 years later: how does it stand in the light of virus evolution?
SUMMARY Fifty years ago, David Baltimore published a brief conceptual paper delineating
the classification of viruses by the routes of genome expression. The six “Baltimore classes” …
the classification of viruses by the routes of genome expression. The six “Baltimore classes” …
Reorganizing the family Parvoviridae: a revised taxonomy independent of the canonical approach based on host association
Parvoviridae, a diverse family of small single-stranded DNA viruses was established in
1975. It was divided into two subfamilies, Parvovirinae and Densovirinae, in 1993 to …
1975. It was divided into two subfamilies, Parvovirinae and Densovirinae, in 1993 to …
Adeno-associated virus capsid assembly is divergent and stochastic
Adeno-associated viruses (AAVs) are increasingly used as gene therapy vectors. AAVs
package their genome in a non-enveloped T= 1 icosahedral capsid of~ 3.8 megaDalton …
package their genome in a non-enveloped T= 1 icosahedral capsid of~ 3.8 megaDalton …
Going viral: virus-based biological control agents for plant protection
The most economically important biotic stresses in crop production are caused by fungi,
oomycetes, insects, viruses, and bacteria. Often chemical control is still the most commonly …
oomycetes, insects, viruses, and bacteria. Often chemical control is still the most commonly …
Twenty-five years of structural parvovirology
Parvoviruses, infecting vertebrates and invertebrates, are a family of single-stranded DNA
viruses with small, non-enveloped capsids with T= 1 icosahedral symmetry. A quarter of a …
viruses with small, non-enveloped capsids with T= 1 icosahedral symmetry. A quarter of a …
Mycoviruses as a part of the global virome: Diversity, evolutionary links and lifestyle
MA Ayllón, EJ Vainio - Advances in virus research, 2023 - Elsevier
Abstract Knowledge of mycovirus diversity, evolution, horizontal gene transfer and shared
ancestry with viruses infecting distantly related hosts, such as plants and arthropods, has …
ancestry with viruses infecting distantly related hosts, such as plants and arthropods, has …
The healthy human virome: from virus–host symbiosis to disease
Viruses are ubiquitous, essential components of any ecosystem, and of multicellular
organism holobionts. Numerous viruses cause acute infection, killing the host or being …
organism holobionts. Numerous viruses cause acute infection, killing the host or being …
Identification of AXL as a co-receptor for human parvovirus B19 infection of human erythroid progenitors
K Ning, W Zou, P Xu, F Cheng, EY Zhang… - Science …, 2023 - science.org
Parvovirus B19 (B19V) infects human erythroid progenitor cells (EPCs) and causes several
hematological disorders and fetal hydrops. Amino acid (aa) 5–68 of minor capsid protein …
hematological disorders and fetal hydrops. Amino acid (aa) 5–68 of minor capsid protein …
Diseases of the giant river prawn Macrobrachium rosenbergii: A review for a growing industry
The giant river prawn, Macrobrachium rosenbergii, is a major focus of aquaculture in tropical
and sub‐tropical regions around the globe. Over the last 30 years, culture of M. rosenbergii …
and sub‐tropical regions around the globe. Over the last 30 years, culture of M. rosenbergii …