Publisher Summary This chapter describes two types of purification methods for Cathepsin
B, Cathepsin H, and Cathepsin L. Method I is applicable to large amounts of frozen tissues …

Cysteine cathepsins belong to the papain-like family C1 of clan CA cysteine peptidases.
These enzymes are ubiquitously expressed and exert their proteolytic activity mainly, but not …

Written by internationally recognized experts, Surimi and Surimi Seafood, Second Edition
provides a wealth of up-to-the-minute information on all aspects of the production of surimi …

Cathepsin B is a lysosomal cysteine protease of the papain family. It functions in intracellular
protein catabolism and in certain situations may also be involved in other physiological …

1. α2-Macroglobulin is known to bind and inhibit a number of serine proteinases. We show
that it binds thiol and carboxyl proteinases, and there is now reason to believe that α2 …

Abstract Benzyloxycarbonyl-phenylalanyl-arginine 4-methyl-7-coumarylamide was found to
be an excellent substrate for the fluorimetric assay of cathepsin B, and arginine 4-methyl-7 …

The degradation of cellular proteins in fibroblasts, both those of rapid and those of slow
turnover rates, was inhibited by low concentrations of chloroquine or neutral red in the …

Abstract Mutation in presenilin 1 (PS1) is one of the leading causes of familial Alzheimer's
disease (fAD). PS1 mutation exacerbates the autophagic and lysosomal pathology in AD …

Studies were designed to explore the possibility that human polymorphonuclear leukocyte
granule constituents in addition to elastase (HLE) had the potential to cause emphysema. A …

Proteinase yscE is the yeast equivalent of the proteasome, a multicatalytic‐multifunctional
proteinase found in higher eukaryotic cells. We have isolated three mutants affecting the …