Molecular and immune landscape of hepatocellular carcinoma to guide therapeutic decision making
Liver cancer, primarily hepatocellular carcinoma (HCC), exhibits highly heterogeneous
histological and molecular aberrations across tumors and within individual tumor nodules …
histological and molecular aberrations across tumors and within individual tumor nodules …
[HTML][HTML] Liquid biopsy: New opportunities for precision medicine in hepatocellular carcinoma care
IMC Aquino, D Pascut - Annals of Hepatology, 2024 - Elsevier
Liquid biopsy, specifically the analysis of circulating tumor DNA (ctDNA), offers a non-
invasive approach for hepatocellular carcinoma (HCC) diagnosis and management …
invasive approach for hepatocellular carcinoma (HCC) diagnosis and management …
Clinical application of circulating tumor DNA in metastatic cancers
Introduction Advances in genomics have facilitated the application of cell-free DNA (cfDNA)
and circulating tumor DNA (ctDNA) in phase II and phase III clinical trials. The various …
and circulating tumor DNA (ctDNA) in phase II and phase III clinical trials. The various …
Personalized MRD Assessment in Perisurgical ctDNA for Prognostic Prediction in Hepatocellular Carcinoma
J Hu, H Tang, CC Jia, XY Zhang, Y Xu… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: Detecting residual disease is a critical clinical requirement in the perisurgical
management of patients with resectable hepatocellular carcinoma (HCC). Previous studies …
management of patients with resectable hepatocellular carcinoma (HCC). Previous studies …
Diagnostic accuracy of ESR1 mutation detection by cell-free DNA in breast cancer: a systematic review and meta-analysis of diagnostic test accuracy
Background Estrogen receptors express in nearly 70% of breast cancers (ER-positive).
Estrogen receptor alpha plays a fundamental role as a significant factor in breast cancer …
Estrogen receptor alpha plays a fundamental role as a significant factor in breast cancer …
Prospects of liquid biopsy in the prognosis and clinical management of gastrointestinal cancers
D Mondal, S Shinde, V Sinha, V Dixit, S Paul… - Frontiers in Molecular …, 2024 - frontiersin.org
Gastrointestinal (GI) cancers account for one-fourth of the global cancer incidence and are
incriminated to cause one-third of cancer-related deaths. GI cancer includes esophageal …
incriminated to cause one-third of cancer-related deaths. GI cancer includes esophageal …
Dissecting intratumor heterogeneity in HCC: new research strategies and clinical implications
S Behrens, XW Wang - Carcinogenesis, 2022 - academic.oup.com
Hepatocellular carcinoma (HCC) accounts for the majority of liver cancers and is driven by a
multitude of viral, metabolic, and lifestyle factors initiating liver injury that subsequently …
multitude of viral, metabolic, and lifestyle factors initiating liver injury that subsequently …
Targeted Molecular Profiling of Circulating Cell-Free DNA in Patients With Advanced Hepatocellular Carcinoma
PURPOSE Next-generation sequencing (NGS) of tumor-derived, circulating cell-free DNA
(cfDNA) may aid in diagnosis, prognostication, and treatment of patients with hepatocellular …
(cfDNA) may aid in diagnosis, prognostication, and treatment of patients with hepatocellular …
Developments and current status of cell‐free DNA in the early detection and management of hepatocellular carcinoma
S Du, K Cao, Y Yan, Y Wang, Z Wang… - Journal of …, 2024 - Wiley Online Library
Nowadays, hepatocellular carcinoma (HCC) is still a major threat to human health globally,
with a disappointing prognosis. Regular monitoring of patients at high risk, utilizing …
with a disappointing prognosis. Regular monitoring of patients at high risk, utilizing …
Current updates on the molecular and genetic signals as diagnostic and therapeutic targets for hepatitis B virus-associated hepatic malignancy
A Adugna, Y Muche, A Melkamu, M Jemal, H Belew… - Heliyon, 2024 - cell.com
Liver cancer caused by the hepatitis B virus (HBV) is the third most common cancer-related
cause of death worldwide. Early detection of HBV-caused hepatic tumors increases the …
cause of death worldwide. Early detection of HBV-caused hepatic tumors increases the …