Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase
superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) …

Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Background Flavored wine is a type of specialized wine fortified with flavor additives such as
herbs, spices, fruits and other natural flavorings, which has attracted increasing attention. In …

Wine polyphenols (PPhs) and volatile organic compounds (VOCs) are responsible for two of
the main sensory characteristics in defining the complexity and quality of red wines …

Ginkgo Biloba leaf extract has been widely used for the prevention and treatment of
thrombosis and cardiovascular disease in both eastern and western countries, but the …

Abstract Background Gegen Qinlian decoction (GQT), is a classic traditional Chinese
medicine formula chronicled in Shang Han Lun, and is widely used to treat diarrhea and …

The genus Sophora (Fabaceae) has been used in traditional medicine for years. Prenylated
flavonoids are one of the constituents of Sophora species that play important roles in their …

Human carboxylesterase 2A (hCES2A) is an important endoplasmic reticulum (ER)-resident
enzyme that is responsible for the hydrolytic metabolism or activation of numerous ester …

Hepatotoxicity occurs as a result of adverse effects of some xenobiotics on the liver, which is
often the target tissue of toxicity for environmental chemicals. Rotenone, used as a natural …

To determine the impact of oral physiology on the volatility of typical wine aroma
compounds, mixtures of a synthetic wine with oral components (centrifuged human saliva …