[HTML][HTML] Investigating the Interplay between Cardiovascular and Neurodegenerative Disease
JP Cousineau, AM Dawe, M Alpaugh - Biology, 2024 - mdpi.com
Simple Summary Traditionally, models of neurodegenerative diseases focus on changes
within the central nervous system. However, growing evidence indicates there are prominent …
within the central nervous system. However, growing evidence indicates there are prominent …
Pharmaceutical and pharmacological studies of Shen Ma Yi Zhi granule for prevention of vascular dementia: A review
S Chang, J Liu, H Li, M Liu, D Shi, L Zhou - Frontiers in Neuroscience, 2022 - frontiersin.org
Background: With dementia significantly increasing hospitalization and disability rates,
worldwide aging of the population presents major challenges to public health. The majority …
worldwide aging of the population presents major challenges to public health. The majority …
ML218 modulates calcium binding protein, oxidative stress, and inflammation during ischemia-reperfusion brain injury in mice
Cerebral ischemia disrupts calcium homeostasis in the brain causing excitotoxicity, oxidative
stress, inflammation, and neuronal cell apoptosis. During ischemic conditions, T-type …
stress, inflammation, and neuronal cell apoptosis. During ischemic conditions, T-type …
Selective inhibition of T-type calcium channel preserves ischemic pre-conditioning mediated neuroprotection during cerebral ischemia reperfusion injury in diabetic …
Ischemic preconditioning (IPC) provides ischemic tolerance and neuroprotection during
cerebral ischemia reperfusion (CI/R) injury. Diabetes abolishes the beneficial effects of …
cerebral ischemia reperfusion (CI/R) injury. Diabetes abolishes the beneficial effects of …
Calcium Channels as a Potential Therapeutic Target for Alzheimer's Disease
Alzheimer's disease (AD) is the most common type of dementia that characterizes the
accumulation of amyloid-β plaques and neurofibrillary tangles in the brain. AD is the most …
accumulation of amyloid-β plaques and neurofibrillary tangles in the brain. AD is the most …
Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats
SA Mkhize, RA Nthlane, SP Xhakaza… - Basic & Clinical …, 2025 - Wiley Online Library
Quercetin is known to reduce blood pressure (BP); however, its acute effects are unclear.
We investigated the acute effects of quercetin on BP, aortic mechanical properties and …
We investigated the acute effects of quercetin on BP, aortic mechanical properties and …
Montelukast Ameliorates 2K1C-Hypertension Induced Endothelial Dysfunction and Associated Vascular Dementia
Background: Declined kidney function associated with hypertension is a danger for cognitive
deficits, dementia, and brain injury. Cognitive decline and vascular dementia (VaD) are …
deficits, dementia, and brain injury. Cognitive decline and vascular dementia (VaD) are …
Flutamide alters markers of inflammation and oxidative stress in experimental model of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder withcomplex etiology
and phenotypes. Many clinical and pre-clinical study have demonstrated the association of …
and phenotypes. Many clinical and pre-clinical study have demonstrated the association of …
Progesterone attenuate autism-like-phenotype through modulation of cerebral inflammation and oxidative stress
Objectives: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that
characterises repetitive behaviour and impairment in social communication as well as …
characterises repetitive behaviour and impairment in social communication as well as …
Mechanisms underlying the therapeutic effects of banxiaxiexin decoction in treating vascular dementia based on network pharmacology and molecular docking
S Liang, L Liu, X Liu, Y Zhang - 2023 - researchsquare.com
Background The Banxiaxiexin decoction constitutes a prevalent Traditional Chinese
Medicine (TCM) formulation employed for the therapeutic intervention of vascular dementia …
Medicine (TCM) formulation employed for the therapeutic intervention of vascular dementia …