Quantifying behavior to understand the brain

TD Pereira, JW Shaevitz, M Murthy - Nature neuroscience, 2020 - nature.com
Over the past years, numerous methods have emerged to automate the quantification of
animal behavior at a resolution not previously imaginable. This has opened up a new field of …

Computational neuroethology: a call to action

SR Datta, DJ Anderson, K Branson, P Perona, A Leifer - Neuron, 2019 - cell.com
The brain is worthy of study because it is in charge of behavior. A flurry of recent technical
advances in measuring and quantifying naturalistic behaviors provide an important …

The connectome of an insect brain

M Winding, BD Pedigo, CL Barnes, HG Patsolic, Y Park… - Science, 2023 - science.org
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

[HTML][HTML] Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish

L Smirnova, BS Caffo, DH Gracias, Q Huang… - Frontiers in …, 2023 - frontiersin.org
Recent advances in human stem cell-derived brain organoids promise to replicate critical
molecular and cellular aspects of learning and memory and possibly aspects of cognition in …

Whole-brain annotation and multi-connectome cell ty** of Drosophila

P Schlegel, Y Yin, AS Bates, S Dorkenwald, K Eichler… - Nature, 2024 - nature.com
The fruit fly Drosophila melanogaster has emerged as a key model organism in
neuroscience, in large part due to the concentration of collaboratively generated molecular …

Using DeepLabCut for 3D markerless pose estimation across species and behaviors

T Nath, A Mathis, AC Chen, A Patel, M Bethge… - Nature protocols, 2019 - nature.com
Noninvasive behavioral tracking of animals during experiments is critical to many scientific
pursuits. Extracting the poses of animals without using markers is often essential to …

Fast animal pose estimation using deep neural networks

TD Pereira, DE Aldarondo, L Willmore, M Kislin… - Nature …, 2019 - nature.com
The need for automated and efficient systems for tracking full animal pose has increased
with the complexity of behavioral data and analyses. Here we introduce LEAP (LEAP …

Network neuroscience

DS Bassett, O Sporns - Nature neuroscience, 2017 - nature.com
Despite substantial recent progress, our understanding of the principles and mechanisms
underlying complex brain function and cognition remains incomplete. Network neuroscience …

Revealing the structure of pharmacobehavioral space through motion sequencing

AB Wiltschko, T Tsukahara, A Zeine, R Anyoha… - Nature …, 2020 - nature.com
Understanding how genes, drugs and neural circuits influence behavior requires the ability
to effectively organize information about similarities and differences within complex …

The Mouse Action Recognition System (MARS) software pipeline for automated analysis of social behaviors in mice

C Segalin, J Williams, T Karigo, M Hui, M Zelikowsky… - Elife, 2021 - elifesciences.org
The study of naturalistic social behavior requires quantification of animals' interactions. This
is generally done through manual annotation—a highly time-consuming and tedious …