Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Mental health profoundly impacts inflammatory responses in the body. This is particularly
apparent in inflammatory bowel disease (IBD), in which psychological stress is associated …

Inflammation is an integral part of animal biology. It provides critical protection from adverse
environmental factors by enforcing the defense of homeostasis and the functional and …

IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

The nervous and immune systems are intricately linked. Although psychological stress is
known to modulate immune function, mechanistic pathways linking stress networks in the …

Over the last 10 years, there has been a growing interest in the relationship between gut
microbiota, the brain, and neurologic-associated affections. As multiple preclinical and …

There is a growing interest in understanding tissue organization, homeostasis, and
inflammation. However, despite an abundance of data, the organizing principles of tissue …

Cytokine release syndrome (CRS) is a major cause of the multi-organ injury and fatal
outcome induced by SARS-CoV-2 infection in severe COVID-19 patients. Metabolism can …

Anxiety-associated symptoms following acute stress usually become extinct gradually within
a period of time. However, the mechanisms underlying how individuals cope with stress to …