Microneedle biomedical devices

M Zheng, T Sheng, J Yu, Z Gu, C Xu - Nature Reviews Bioengineering, 2024 - nature.com
Microneedle (MN) technologies have gained interest for biomedical applications, ranging
from drug delivery to sensing and tissue sampling in skin and internal organs. The …

Strategies to develop polymeric microneedles for controlled drug release

BZ Chen, YT He, ZQ Zhao, YH Feng, L Liang… - Advanced Drug Delivery …, 2023 - Elsevier
The remarkable appeal of microneedle controlled-release systems has captivated both the
academic community and pharmaceutical industry due to their great potential for achieving …

Bioinspired adaptable indwelling microneedles for treatment of diabetic ulcers

X Zhang, J Gan, L Fan, Z Luo, Y Zhao - Advanced Materials, 2023 - Wiley Online Library
Microneedles provide an effective strategy for transdermal drug delivery. Many endeavors
have been devoted to develo** smart microneedles that can respond to and interact with …

Blue-ringed octopus-inspired microneedle patch for robust tissue surface adhesion and active injection drug delivery

Z Zhu, J Wang, X Pei, J Chen, X Wei, Y Liu, P **a… - Science …, 2023 - science.org
Intratissue topical medication is important for the treatment of cutaneous, mucosal or
splanchnic diseases. However, penetrating surface barriers to providing adequate and …

Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems

DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Self‐Heating Multistage Microneedle Patch for Topical Therapy of Skin Cancer

J Shao, X Li, Y Li, J Lin, P Huang - Advanced Materials, 2024 - Wiley Online Library
Topical therapy is a favored route for treating skin cancers, but remain many challenges,
such as low delivery efficiency, limited tumor tissue penetration, and unsatisfactory blood …

Nature-inspired adhesive systems

M Li, A Mao, Q Guan, E Saiz - Chemical Society Reviews, 2024 - pubs.rsc.org
Many organisms in nature thrive in intricate habitats through their unique bio-adhesive
surfaces, facilitating tasks such as capturing prey and reproduction. It's important to note that …

[HTML][HTML] A review of 3D-printing of microneedles

M Olowe, SK Parupelli, S Desai - Pharmaceutics, 2022 - mdpi.com
Microneedles are micron-sized devices that are used for the transdermal administration of a
wide range of active pharmaceutics substances with minimally invasive pain. In the past …