Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the
eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot …

Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …

The development of multiple chromosome-scale reference genome sequences in many
taxonomic groups has yielded a high-resolution view of the patterns and processes of …

В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …

The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …

Incomplete lineage sorting (ILS) makes ancestral genetic polymorphisms persist during
rapid speciation events, inducing incongruences between gene trees and species trees. ILS …

The inability to predict long noncoding RNAs from genomic sequence has impeded the use
of comparative genomics for studying their biology. Here, we develop methods that use RNA …

Birds are the most species-rich class of tetrapod vertebrates and have wide relevance
across many research fields. We explored bird macroevolution using full genomes from 48 …

Transposable elements (TEs) are conventionally identified in eukaryotic genomes by
alignment to consensus element sequences. Using this approach, about half of the human …

Transposable elements (TEs) are genetic elements with the ability to mobilize and replicate
themselves in a genome. Mammalian genomes are dominated by TEs, which can reach …