Challenges and opportunities in antimicrobial stewardship among hematopoietic stem cell transplant and oncology patients

A Majumdar, MR Shah, JJ Park, N Narayanan… - Antibiotics, 2023 - mdpi.com
Antimicrobial stewardship programs play a critical role in optimizing the use of antimicrobials
against pathogens in the era of growing multi-drug resistance. However, implementation of …

The feasibility and generalizability of assessing the appropriateness of antimicrobial prescribing in hospitals: a review of the Australian National Antimicrobial …

R James, Y Nakamachi, A Morris, M So… - JAC-Antimicrobial …, 2022 - academic.oup.com
Abstract The National Antimicrobial Prescribing Survey (NAPS) is a web-based qualitative
auditing platform that provides a standardized and validated tool to assist hospitals in …

[18F] FDG-PET-CT compared with CT for persistent or recurrent neutropenic fever in high-risk patients (PIPPIN): a multicentre, open-label, phase 3, randomised …

A Douglas, K Thursky, T Spelman, J Szer… - The Lancet …, 2022 - thelancet.com
Background Management of neutropenic fever in high-risk haematology patients is
challenging; there are often few localising clinical features, and diagnostic tests have poor …

Antimicrobial stewardship in immunocompromised patients: current state and future opportunities

J Hand, H Imlay - Infectious Disease Clinics, 2023 - id.theclinics.com
Antimicrobial stewardship programs (ASPs) coordinate strategies to optimize antimicrobial
prescribing and limit antimicrobial-associated adverse effects. The positive impact of ASPs …

New approaches to management of fever and neutropenia in high-risk patients

A Douglas, K Thursky, M Slavin - Current Opinion in Infectious …, 2022 - journals.lww.com
Acute leukaemic and autologous HCT patients with resolved neutropenic fever prior to count
recovery can have empiric therapy safely discontinued or de-escalated. There is an …

Fluoroquinolone prophylaxis in patients with neutropenia at high risk of serious infections: Exploring pros and cons

N Singh, K Thursky, G Maron… - Transplant Infectious …, 2023 - Wiley Online Library
Background The use of fluoroquinolones to prevent infections in neutropenic patients with
cancer or undergoing hematopoietic stem cell transplantation (HSCT) is a controversial …

[HTML][HTML] Indications for medical antibiotic prophylaxis and potential targets for antimicrobial stewardship intervention: a narrative review

P Ioannou, S Karakonstantis, J Schouten… - Clinical Microbiology …, 2022 - Elsevier
Background Most of the antimicrobial stewardship (AMS) literature has focused on
antimicrobial consumption for the treatment of infections, for the prophylaxis of surgical site …

Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them

M So, H Tsai, N Swaminathan… - … Stewardship & Healthcare …, 2022 - cambridge.org
Antimicrobial therapies are essential tools for transplant recipients who are at high risk for
infectious complications. However, judicious use of antimicrobials is critical to preventing the …

Antimicrobial use and appropriateness in neutropenic fever: a study of the Hospital National Antimicrobial Prescribing Survey data

N Singh, AP Douglas, MA Slavin… - Journal of …, 2024 - academic.oup.com
Background Neutropenic fever (NF) is a common complication in patients receiving
chemotherapy. Judicious antimicrobial use is paramount to minimize morbidity and mortality …

Validation of the antifungal national antimicrobial prescribing survey (AF-NAPS) quality assessment tool

A Khanina, AP Douglas, DK Yeoh, M So… - Journal of …, 2023 - academic.oup.com
Abstract Background The Antifungal National Antimicrobial Prescribing Survey (AF-NAPS)
was developed to undertake streamlined quality audits of antifungal prescribing. The validity …