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[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …
amphiphilic polymers, represent an innovative tool to overcome several issues related to …
Artificial intelligence and machine learning in computational nanotoxicology: unlocking and empowering nanomedicine
Advances in nanomedicine, coupled with novel methods of creating advanced materials at
the nanoscale, have opened new perspectives for the development of healthcare and …
the nanoscale, have opened new perspectives for the development of healthcare and …
[HTML][HTML] Phytosomal nanocarriers as platforms for improved delivery of natural antioxidant and photoprotective compounds in propolis: An approach for enhanced both …
Propolis has been reported to possess rich content of antioxidant compounds and may
provide health benefits through oxidative stress reduction. Presently, the formulation …
provide health benefits through oxidative stress reduction. Presently, the formulation …
Physiologically based pharmacokinetic modeling of nanoparticles
Nanoparticles are frequently designed to improve the pharmacokinetics profiles and tissue
distribution of small molecules to prolong their systemic circulation, target specific tissue, or …
distribution of small molecules to prolong their systemic circulation, target specific tissue, or …
Integration of in vitro and in vivo models to predict cellular and tissue dosimetry of nanomaterials using physiologically based pharmacokinetic modeling
Nanomaterials (NMs) have been increasingly used in a number of areas, including
consumer products and nanomedicine. Target tissue dosimetry is important in the evaluation …
consumer products and nanomedicine. Target tissue dosimetry is important in the evaluation …
Nanomedicines-tiny particles and big challenges
MRC Marques, Q Choo, M Ashtikar, TC Rocha… - Advanced Drug Delivery …, 2019 - Elsevier
After decades of research, nanotechnology has been used in a broad array of biomedical
products including medical devices, drug products, drug substances, and pharmaceutical …
products including medical devices, drug products, drug substances, and pharmaceutical …
Opportunities and challenges of physiologically based pharmacokinetic modeling in drug delivery
W Wang, D Ouyang - Drug Discovery Today, 2022 - Elsevier
Highlights•PBPK modeling bridges drug properties and PK behaviours in drug discovery
and development.•The PBPK is often used in oral formulation development, to address …
and development.•The PBPK is often used in oral formulation development, to address …
Effects of nanoplastics on clam Ruditapes philippinarum at environmentally realistic concentrations: toxicokinetics, toxicity, and gut microbiota
Nanoplastics are ubiquitous in marine environments, understanding to what extent
nanoplastics accumulate in bivalves and the adverse effects derived from their retention is …
nanoplastics accumulate in bivalves and the adverse effects derived from their retention is …
Nanomedicine at the crossroads–a quick guide for IVIVC
For many years, nanomedicine is pushing the boundaries of drug delivery. When applying
these novel therapeutics, safety considerations are not only a key concern when entering …
these novel therapeutics, safety considerations are not only a key concern when entering …
Nanopharmaceuticals for wound healing–lost in translation?
Today, many of the newly developed pharmaceuticals and medical devices take advantage
of nanotechnology and with a rising incidence of chronic diseases such as diabetes and …
of nanotechnology and with a rising incidence of chronic diseases such as diabetes and …