[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review

M van Elk, DB Yaden - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Psychedelics and other psychoplastogens for treating mental illness

MV Vargas, R Meyer, AA Avanes, M Rus… - Frontiers in …, 2021 - frontiersin.org
Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

The subjective effects of psychedelics may not be necessary for their enduring therapeutic effects

DE Olson - ACS Pharmacology & Translational Science, 2020 - ACS Publications
Psychedelics represent one of the most promising classes of experimental medicines for the
treatment of neuropsychiatric disorders due to their ability to promote neural plasticity and …

Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

F Cavanna, S Muller, LA de la Fuente… - Translational …, 2022 - nature.com
The use of low sub-perceptual doses of psychedelics (“microdosing”) has gained popularity
in recent years. Although anecdotal reports claim multiple benefits associated with this …

[HTML][HTML] The emerging science of microdosing: A systematic review of research on low dose psychedelics (1955–2021) and recommendations for the field

V Polito, P Liknaitzky - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
The use of low doses of psychedelic substances (microdosing) is attracting increasing
interest. This systematic review summarises all empirical microdosing research to date …

Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing

LS Kaertner, MB Steinborn, H Kettner, MJ Spriggs… - Scientific reports, 2021 - nature.com
Psychedelic microdosing describes the ingestion of near-threshold perceptible doses of
classic psychedelic substances. Anecdotal reports and observational studies suggest that …

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers

JM Rootman, P Kryskow, K Harvey, P Stamets… - Scientific reports, 2021 - nature.com
The use of psychedelic substances at sub-sensorium 'microdoses', has gained popular
academic interest for reported positive effects on wellness and cognition. The present study …

Adolescent and adult time trends in US hallucinogen use, 2002–19: Any use, and use of ecstasy, LSD and PCP

O Livne, D Shmulewitz, C Walsh, DS Hasin - Addiction, 2022 - Wiley Online Library
Abstract Background and Aims Hallucinogen use is potentially harmful. Information on
whether such use has increased in recent decades is lacking. This study assessed overall …

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls

JM Rootman, M Kiraga, P Kryskow, K Harvey… - Scientific Reports, 2022 - nature.com
Psilocybin microdosing involves repeated self-administration of mushrooms containing
psilocybin at doses small enough to not impact regular functioning. Microdose practices are …

Psilocybin microdosing does not affect emotion-related symptoms and processing: A preregistered field and lab-based study

J Marschall, G Fejer, P Lempe… - Journal of …, 2022 - journals.sagepub.com
Background: Microdoses of psychedelics (ie a sub-hallucinogenic dose taken every third
day) can reduce symptoms of depression, anxiety and stress according to anecdotal reports …