Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that govern the
expression of genes responsible for energy metabolism, cellular development, and …

Liposarcomas are rare malignant tumors of adipocytic differentiation. The classification of
liposarcomas into four principal subtypes reflects the distinct clinical behavior, treatment …

Regulatory role of Sirtuin 1 (SIRT1), one of the most extensively studied members of its kind
in histone deacetylase family in governing multiple cellular fates, is predominantly linked to …

Cancer cell plasticity facilitates the development of therapy resistance and malignant
progression. De-differentiation processes, such as an epithelial-mesenchymal transition …

Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

In this note, we present a detailed procedure for highly effective and reproducible 3T3-L1
cell differentiation. Due to their potential to differentiate from fibroblasts to adipocytes, 3T3 …

▪ Abstract The peroxisome proliferator-activated receptors (PPARs) are a group of three
nuclear receptor isoforms, PPARγ, PPARα, and PPARδ, encoded by different genes. PPARs …