Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …

Mycobacterium tuberculosis has thrived in parallel with humans for millennia, and despite
our efforts, M. tuberculosis continues to plague us, currently infecting a third of the world's …

Mycobacterium tuberculosis (M. tb) is an intracellular pathogen that exploits moonlighting
functions of its proteins to interfere with host cell functions. PE/PPE proteins utilize host …

The human pathogen Mycobacterium tuberculosis (Mtb) harbors a well-orchestrated Clp
(caseinolytic protease) proteolytic machinery consisting of two oligomeric segments, a barrel …

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis
(Mtb), and its incidence and mortality are increasing. The BCG vaccine was developed in the …

Mycobacterium tuberculosis (M. tb) is a successful pathogen that can reside within the
alveolar macrophages of the host and can survive in a latent stage. The pathogen has …

Permeation through bacterial cells for exchange or uptake of biomolecules and ions
invariably depend upon the existence of pore-forming proteins (porins) in their outer …

Intrinsic disorder in proteins resulting in considerable variation in structure can lead to
multiple functions including multi-specificity and diverse pathologies. Protein interfaces can …

Introduction Neutrophil granulocytes predominate in the lungs of patients infected with
Mycobacterium tuberculosis (Mtb) in earlier stages of the disease. During infection …

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (M.
tuberculosis), mainly transmitted through droplets to infect the lungs, and seriously affecting …