Recent investigations in bacteria suggest that membraneless organelles play a crucial role
in the subcellular organization of bacterial cells. However, the biochemical functions and …

Proper chromosome segregation during cell division is essential in all domains of life. In the
majority of bacterial species, faithful chromosome segregation is mediated by the tripartite …

During cell division, newly replicated DNA is actively segregated to the daughter cells. In
most bacteria, this process involves the DNA-binding protein ParB, which condenses the …

Liquid-liquid phase-separated (LLPS) states are key to compartmentalizing components in
the absence of membranes; however, it is unclear whether LLPS condensates are actively …

Genome dynamics are intimately linked to the regulation of gene expression, the most
fundamental mechanism in biology, yet we still do not know whether the very process of …

In most bacteria, chromosome segregation is driven by the ParAB S system where the
CTPase protein ParB loads at the parS site to trigger the formation of a large partition …

ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and
archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking …

The ParAB S system is essential for prokaryotic chromosome segregation. After loading at
parS on the genome, ParB (partition protein B) proteins rapidly redistribute to distances of …

Numerous examples of microbial phase-separated biomolecular condensates have now
been identified following advances in fluorescence imaging and single molecule microscopy …

In all living organisms, it is essential to transmit genetic information faithfully to the next
generation. The SMC-ParAB-parS system is widely employed for chromosome segregation …