Biomarkers in acute kidney injury–pathophysiological basis and clinical performance
Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …
the recent past. These molecules can be detected in urine or blood and signify structural …
Biomarkers of acute kidney injury: the pathway from discovery to clinical adoption
Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …
[HTML][HTML] Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus …
Over the last decade there has been considerable progress in the discovery and
development of biomarkers of kidney disease, and several have now been evaluated in …
development of biomarkers of kidney disease, and several have now been evaluated in …
The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer
Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …
Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature
J Vanmassenhove, R Vanholder… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Acute kidney injury (AKI) remains associated with high morbidity and mortality,
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …
Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status
A Haase-Fielitz, M Haase… - Annals of clinical …, 2014 - journals.sagepub.com
Background The early prediction of acute kidney injury (AKI) by current clinical and
laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) …
laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) …
Neutrophil gelatinase‐associated lipocalin: pathophysiology and clinical applications
Neutrophil gelatinase‐associated lipocalin (NGAL), a 25 kDa protein produced by injured
nephron epithelia, is one of the most promising new markers of renal epithelial injury. In …
nephron epithelia, is one of the most promising new markers of renal epithelial injury. In …
The role of biomarkers in acute kidney injury
N Srisawat, JA Kellum - Critical care clinics, 2020 - criticalcare.theclinics.com
In the past 50 years, the diagnosis of acute kidney injury (AKI) has been mainly based on
serum creatinine. 1 It is well known that an increase in serum creatinine level occurs after a …
serum creatinine. 1 It is well known that an increase in serum creatinine level occurs after a …
Molecular nephrology: types of acute tubular injury
The acute loss of kidney function has been diagnosed for many decades using the serum
concentration of creatinine—a muscle metabolite that is an insensitive and non-specific …
concentration of creatinine—a muscle metabolite that is an insensitive and non-specific …
Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study
Objectives: This study aimed to determine the diagnostic and prognostic value of urinary
biomarkers of intrinsic acute kidney injury (AKI) when patients were triaged in the …
biomarkers of intrinsic acute kidney injury (AKI) when patients were triaged in the …