Bioprinting technologies are powerful additive biofabrication techniques to produce cellular
constructs for skin tissue engineering owing to their unique ability to precisely pattern living …

Background: Wound healing is a dynamic process whereby cells, growth factors (GFs), and
the extracellular matrix (ECM) interact to restore the architecture of damaged tissue. Chronic …

Application of reconstructed human Skin (RhS) is a promising approach for the treatment of
extensive wounds and for drug efficacy and safety testing. However, incorporating …

Introduction: An autologous split-thickness skin graft (STSG) is a standard treatment for
coverage of full-thickness skin defects. However, this technique has two major drawbacks …

Many cell-based regenerative medicine strategies toward tissue-engineered constructs are
currently being explored. Cell–cell interactions and interactions with different biomaterials …

Mixed arterial venous disease is estimated to affect up to 26% of patients with lower
extremity ulcerations. However, its clinical significance and pathophysiology are …

A variety of skin substitutes that restore epidermal and dermal structures are currently
available on the market. However, the main focus in research and clinical application lies on …

Purpose: Oral soft tissue augmentation or grafting procedures are often necessary to
achieve proper wound closure after deficits resulting from tumor excision, clefts, trauma …

A wound is a disruption of the normal structure and function of the skin and soft tissue
architecture [1]. An acute wound demonstrates normal physiology, and healing is anticipated …

There is a high incidence of failure and recurrence for chronic skin wounds following
conventional therapies. To promote healing, the use of skin substitutes containing living …