Haemonchosis in Sheep and Goats, Control Strategies and Development of Vaccines against Haemonchus contortus

I Adduci, F Sajovitz, B Hinney, K Lichtmannsperger… - Animals, 2022 - mdpi.com
Simple Summary Haemonchus contortus is the most pathogenic blood-feeding parasitic
nematode in sheep and goats, threatening animal welfare and causing tremendous …

Advances in the Development of Anti-Haemonchus contortus Vaccines: Challenges, Opportunities, and Perspectives

M Ehsan, RS Hu, QL Liang, JL Hou, X Song, R Yan… - Vaccines, 2020 - mdpi.com
The gastrointestinal nematode parasite Haemonchus contortus (H. contortus) is a resident of
tropical and subtropical regions worldwide that imposes significant production losses …

Hookworms dynamically respond to loss of Type 2 immune pressure

AA Ferguson, JM Inclan-Rico, D Lu, SD Bobardt… - PLoS …, 2023 - journals.plos.org
The impact of the host immune environment on parasite transcription and fitness is currently
unknown. It is widely held that hookworm infections have an immunomodulatory impact on …

The Proteome and Lipidome of Extracellular Vesicles from Haemonchus contortus to Underpin Explorations of Host–Parasite Cross–Talk

T Wang, TF Koukoulis, LJ Vella, H Su… - International Journal of …, 2023 - mdpi.com
Many parasitic worms have a major adverse impact on human and animal populations
worldwide due to the chronicity of their infections. There is a growing body of evidence …

Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868

AC Taki, T Wang, NN Nguyen, CS Ang… - Frontiers in …, 2022 - frontiersin.org
Parasitic roundworms (nematodes) cause destructive diseases, and immense suffering in
humans and other animals around the world. The control of these parasites relies heavily on …

High-quality nuclear genome for Sarcoptes scabiei—A critical resource for a neglected parasite

PK Korhonen, RB Gasser, G Ma, T Wang… - PLoS Neglected …, 2020 - journals.plos.org
The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin
of humans and animals worldwide. In humans, this mite causes a neglected tropical disease …

A member of the CAP protein superfamily, Hc-CAP-15, is important for the parasitic-stage development of Haemonchus contortus

H Liu, Z Tao, Y Wang, X Liu, C Wang, L Liu, M Hu - Parasites & Vectors, 2023 - Springer
Background The CAP superfamily proteins are distributed widely in eukaryotes and play
crucial roles in various biological processes. However, very little is known about their …

A high-throughput phenotypic screen of the 'Pandemic Response Box'identifies a quinoline derivative with significant anthelmintic activity

HT Shanley, AC Taki, JJ Byrne, A Jabbar, TNC Wells… - Pharmaceuticals, 2022 - mdpi.com
Parasitic nematodes cause diseases in livestock animals and major economic losses to the
agricultural industry worldwide. Nematodes of the order Strongylida, including Haemonchus …

Mining nematode protein secretomes to explain lifestyle and host specificity

L Tritten, C Ballesteros, R Beech… - PLoS Neglected …, 2021 - journals.plos.org
Parasitic nematodes are highly successful pathogens, inflicting disease on humans, animals
and plants. Despite great differences in their life cycles, host preference and transmission …

[HTML][HTML] Chromosome-contiguous genome for the Haecon-5 strain of Haemonchus contortus reveals marked genetic variability and enables the discovery of essential …

Y Zheng, ND Young, TL Campos, PK Korhonen… - International Journal for …, 2024 - Elsevier
Millions of livestock animals worldwide are infected with the haematophagous barber's pole
worm, Haemonchus contortus, the aetiological agent of haemonchosis. Despite the major …