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Engineering precision nanoparticles for drug delivery
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …
advances, but technophilic expectations and technophobic demands must be …
Delivery technologies for cancer immunotherapy
Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …
Blood-brain barrier and delivery of protein and gene therapeutics to brain
WM Pardridge - Frontiers in aging neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) and treatment of the brain in aging require the development of
new biologic drugs, such as recombinant proteins or gene therapies. Biologics are large …
new biologic drugs, such as recombinant proteins or gene therapies. Biologics are large …
In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers
TT Smith, SB Stephan, HF Moffett, LE McKnight… - Nature …, 2017 - nature.com
An emerging approach for treating cancer involves programming patient-derived T cells with
genes encoding disease-specific chimeric antigen receptors (CARs), so that they can …
genes encoding disease-specific chimeric antigen receptors (CARs), so that they can …
Ligand‐installed nanocarriers toward precision therapy
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …
Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers
Tumor-associated macrophages (TAMs) usually express an M2 phenotype, which enables
them to perform immunosuppressive and tumor-promoting functions. Reprogramming these …
them to perform immunosuppressive and tumor-promoting functions. Reprogramming these …
Glioblastoma: current status, emerging targets, and recent advances
Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …
population of genetically unstable and highly infiltrative cells that are resistant to …
ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma
W Mao, K Wang, B Xu, H Zhang, S Sun, Q Hu, L Zhang… - Molecular Cancer, 2021 - Springer
Circular RNAs are a new class of non-coding RNAs that have been shown to play critical
roles in the development and progression of renal cell carcinoma (RCC). However, little is …
roles in the development and progression of renal cell carcinoma (RCC). However, little is …
Therapeutic applications of nanobiotechnology
Y Dutt, RP Pandey, M Dutt, A Gupta, A Vibhuti… - Journal of …, 2023 - Springer
Nanobiotechnology, as a novel and more specialized branch of science, has provided a
number of nanostructures such as nanoparticles, by utilizing the methods, techniques, and …
number of nanostructures such as nanoparticles, by utilizing the methods, techniques, and …