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Zoonosis and zooanthroponosis of emerging respiratory viruses
Lung infections in Influenza-Like Illness (ILI) are triggered by a variety of respiratory viruses.
All human pandemics have been caused by the members of two major virus families …
All human pandemics have been caused by the members of two major virus families …
SARS-CoV-2 and the DNA damage response
RJ Grand - Journal of General Virology, 2023 - microbiologyresearch.org
The recent coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is characterized by …
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is characterized by …
Unraveling the role of the nucleocapsid protein in SARS-CoV-2 pathogenesis: From viral life cycle to vaccine development
YA El-Maradny, MA Badawy, KI Mohamed… - International Journal of …, 2024 - Elsevier
Background The nucleocapsid protein (N protein) is the most abundant protein in SARS-
CoV-2. Viral RNA and this protein are bound by electrostatic forces, forming cytoplasmic …
CoV-2. Viral RNA and this protein are bound by electrostatic forces, forming cytoplasmic …
Genomic Surveillance and Mutation Analysis of SARS-CoV-2 Variants among Patients in Saudi Arabia
The genome of severe acute respiratory coronavirus-2 (SARS-CoV-2), the virus responsible
for coronavirus disease 2019 (COVID-19), has undergone a rapid evolution, resulting in the …
for coronavirus disease 2019 (COVID-19), has undergone a rapid evolution, resulting in the …
Analysis of the structure and interactions of the SARS-CoV-2 ORF7b accessory protein
SARS-CoV-2 carries a sizeable number of proteins that are accessory to replication but may
be essential for virus–host interactions and modulation of the host immune response. Here …
be essential for virus–host interactions and modulation of the host immune response. Here …
3-chymotrypsin-like protease in SARS-CoV-2
K Al Adem, JC Ferreira, AJ Villanueva, S Fadl… - Bioscience …, 2024 - portlandpress.com
Coronaviruses constitute a significant threat to the human population. Severe acute
respiratory syndrome coronavirus-2, SARS-CoV-2, is a highly pathogenic human …
respiratory syndrome coronavirus-2, SARS-CoV-2, is a highly pathogenic human …
A multifaceted approach for identification, validation, and immunogenicity of naturally processed and in silico-predicted highly conserved SARS-CoV-2 peptides
SARS-CoV-2 remains a major global public health concern. Antibody waning and immune
escape variant emergence necessitate the development of next generation vaccines that …
escape variant emergence necessitate the development of next generation vaccines that …
[HTML][HTML] Inhalation phage therapy as a new approach to preventing secondary bacterial pneumonia in patients with moderate to severe COVID-19: A double-blind …
HR Samaee, G Eslami, G Rahimzadeh… - Journal of Drug Delivery …, 2023 - Elsevier
Inhalation phage therapy is proposed as a replacement approach for antibiotics in the
treatment of pulmonary bacterial infections. This study investigates phage therapy on …
treatment of pulmonary bacterial infections. This study investigates phage therapy on …
[HTML][HTML] Advances in the Search for SARS-CoV-2 Mpro and PLpro Inhibitors
MA Diogo, AGT Cabral, RB de Oliveira - Pathogens, 2024 - mdpi.com
SARS-CoV-2 is a spherical, positive-sense, single-stranded RNA virus with a large genome,
responsible for encoding both structural proteins, vital for the viral particle's architecture, and …
responsible for encoding both structural proteins, vital for the viral particle's architecture, and …
An isothermal calorimetry assay for determining steady state kinetic and Ensitrelvir inhibition parameters for SARS-CoV-2 3CL-protease
L Mazzei, S Ranieri, D Silvestri, R Greene-Cramer… - Scientific Reports, 2024 - nature.com
This manuscript details the application of Isothermal Titration Calorimetry (ITC) to
characterize the kinetics of 3CLpro, the main protease from the Severe Acute Respiratory …
characterize the kinetics of 3CLpro, the main protease from the Severe Acute Respiratory …