Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …

Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as
sha** cancer immunosurveillance and response to immunotherapy. Our understanding of …

Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

An inflammatory microenvironment, either conferred by an underlying chronic overt or
smoldering inflammatory condition constitutes a prerequisite and fuel to essentially all …

Metabolic reprogramming in cancer is not only a biological hallmark but also reveals
treatment vulnerabilities. Numerous metabolic molecules have shown promise as treatment …

In tumor-bearing mice, cyclic fasting or fasting-mimicking diets (FMD) enhance the activity of
antineoplastic treatments by modulating systemic metabolism and boosting antitumor …

Despite the promising advances in novel cancer therapy such as immune checkpoint
inhibitors (ICIs), limitations including therapeutic resistance and toxicity remain. In recent …

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Our understanding of how the microbiota affects the balance between response to and
failure of cancer treatment by modulating the tumour microenvironment and systemic …