The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Correlates of protection against SARS‐CoV‐2 infection and COVID‐19 disease

D Goldblatt, G Alter, S Crotty… - Immunological reviews, 2022 - Wiley Online Library
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …

Global landscape of SARS-CoV-2 genomic surveillance and data sharing

Z Chen, AS Azman, X Chen, J Zou, Y Tian, R Sun… - Nature …, 2022 - nature.com
Genomic surveillance has shaped our understanding of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS …

[HTML][HTML] Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single …

G Zeng, Q Wu, H Pan, M Li, J Yang, L Wang… - The Lancet Infectious …, 2022 - thelancet.com
Background Large-scale vaccination against COVID-19 is being implemented in many
countries with CoronaVac, an inactivated vaccine. We aimed to assess the immune …

Effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern: a systematic review and meta-analysis

B Zeng, L Gao, Q Zhou, K Yu, F Sun - BMC medicine, 2022 - Springer
Background It was urgent and necessary to synthesize the evidence for vaccine
effectiveness (VE) against SARS-CoV-2 variants of concern (VOC). We conducted a …

SARS-CoV-2-specific antibody and T-cell responses 1 year after infection in people recovered from COVID-19: a longitudinal cohort study

L Guo, G Wang, Y Wang, Q Zhang, L Ren, X Gu… - The Lancet …, 2022 - thelancet.com
Background The memory immune response is crucial for preventing reinfection or reducing
disease severity. However, the robustness and functionality of the humoral and T-cell …

Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

L Renia, YS Goh, A Rouers, N Le Bert, WN Chia… - Nature …, 2022 - nature.com
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …

[HTML][HTML] A systematic review of vaccine breakthrough infections by SARS-CoV-2 delta variant

M Zhang, Y Liang, D Yu, B Du, W Cheng… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Vaccines are proving to be highly effective in controlling hospitalization and deaths
associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

[HTML][HTML] SARS-CoV-2 variants–evolution, spike protein, and vaccines

KWK Chen, DTN Huang, LM Huang - biomedical journal, 2022 - Elsevier
Abstracts Despite the rising natural and vaccines mediated immunity, several countries have
experienced a resurgence of the Coronavirus disease of 2019 (COVID-19) due to the …

Antibody titers and protection against Omicron (BA. 1 and BA. 2) SARS-CoV-2 infection

C Dimeglio, M Migueres, N Bouzid, S Chapuy-Regaud… - Vaccines, 2022 - mdpi.com
The emergence of the SARS-CoV-2 variants of concern has greatly influenced the immune
correlates of protection, and there are little data about the antibody threshold concentrations …