Transition-metal and solvent-free oxidative C–H fluoroalkoxylation of quinoxalinones with fluoroalkyl alcohols

J Xu, H Yang, H Cai, H Bao, W Li, P Zhang - Organic letters, 2019 - ACS Publications
The first example of oxidative C–H fluoroalkoxylation of quinoxalinones with fluoroalkyl
alcohols under transition-metal and solvent-free conditions is described. This approach …

Transition Metal‐Catalyzed Transformations of Chalcones

CMM Santos, AMS Silva - The Chemical Record, 2024 - Wiley Online Library
Chalcones are a class of naturally occurring flavonoid compounds associated to a variety of
biological and pharmacological properties. Several reviews have been published describing …

N-Trifluoroethoxy Benzotriazolium Triflate: A Readily Available Reagent for Direct Radical Trifluoroethoxylation of Alkenes

M Chen, Y Lu, Y Shen, Q Wang - Organic Letters, 2024 - ACS Publications
Herein, we describe the development and application of a novel benzotriazole-based
reagent toward radical trifluoroethoxylation. Various alkene classes, including styrene …

Synthesis of fluorinated alkyl aryl ethers by palladium-catalyzed C–O cross-coupling

R Szpera, PG Isenegger, M Ghosez… - Organic …, 2020 - ACS Publications
Herein, we report a highly effective protocol for the cross-coupling of (hetero) aryl bromides
with fluorinated alcohols using the commercially available precatalyst tBuBrettPhos Pd G3 …

Synthesis of Aryl‐and Heteroaryl‐Trifluoroethyl Ethers: Aims, Challenges and New Methodologies

B Pethő, Z Novák - Asian Journal of Organic Chemistry, 2019 - Wiley Online Library
Fluorinated substances have outstanding importance in most fields of the chemical industry,
from agrochemicals and material science to pharmaceutical research. Although aryl‐and …

Rh-Catalyzed oxidation and trifluoroethoxylation of N-aryl-pyrrolidin-2-ones: a domino approach for the synthesis of N-aryl-5-(2, 2, 2-trifluoroethoxy)-1, 5-dihydro-2 H …

Y Luo, M Hu, J Ge, B Li, L He - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
The synthesis of trifluoroethoxylated dihydropyrrolidones via rhodium-catalyzed oxidation
and trifluoroethoxylation of pyrrolidones is presented in this paper. This process realized the …

Palladium-Catalyzed C–H Trifluoroethoxylation of N-Sulfonylbenzamides

L Yang, S Li, L Cai, Y Ding, L Fu, Z Cai, H Ji, G Li - Organic letters, 2017 - ACS Publications
The trifluoroethyl aryl ethers are important motifs in drug molecules. However, a report
devoted specifically to the study of transition-metal-catalyzed C–H trifluoroethoxylation has …

Copper-Catalyzed Methoxylation of Aryl Bromides with 9-BBN− OMe

JR Wang, ZQ Song, C Li, DH Wang - Organic Letters, 2021 - ACS Publications
A Cu-catalyzed cross-coupling reaction between aryl bromides and 9-BBN–OMe to provide
aryl methyl ethers under mild conditions is reported. The oxalamide ligand BHMPO plays a …

Copper-catalyzed oxidative trifluoroethoxylation of aryl boronic acids with CF3CH2OH

K Zhang, XH Xu, FL Qing - Journal of Fluorine Chemistry, 2017 - Elsevier
Copper-catalyzed oxidative trifluoroethoxylation of aryl boronic acids with CF3CH2OH -
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Synthesis of Polyfluoroalkyl Aryl Ethers Mediated by Sulfuryl Fluoride as a Traceless Activator

C Plaçais, L Wisson, I Chataigner, M Donnard… - Organic …, 2024 - ACS Publications
Herein, we report the metal-free synthesis of polyfluoroalkyl aryl ethers via nucleophilic
substitution of fluorosulfonates, obtained in one pot by bubbling of sulfuryl fluoride (SO2F2) …