[HTML][HTML] Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy
Y Deng, L Qiao, M Du, C Qu, L Wan, J Li, L Huang - Genes & diseases, 2022 - Elsevier
Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …
Molecular pathology of age-related macular degeneration
Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the
world. Although the etiology and pathogenesis of AMD remain largely unclear, a complex …
world. Although the etiology and pathogenesis of AMD remain largely unclear, a complex …
Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration
Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a
major cause of blindness in the developed world. Owing to its complexity and the lack of an …
major cause of blindness in the developed world. Owing to its complexity and the lack of an …
Subretinal drusenoid deposits in non-neovascular age-related macular degeneration: morphology, prevalence, topography, and biogenesis model
Purpose: To characterize the morphology, prevalence, and topography of subretinal
drusenoid deposits, a candidate histological correlate of reticular pseudodrusen, with …
drusenoid deposits, a candidate histological correlate of reticular pseudodrusen, with …
The oil spill in ageing Bruch membrane
Ageing is the largest risk factor for age-related macular degeneration (AMD), and soft drusen
and basal linear deposits are lipid-rich extracellular lesions specific to AMD. Oil red O …
and basal linear deposits are lipid-rich extracellular lesions specific to AMD. Oil red O …
Cholesterol in the retina: the best is yet to come
IA Pikuleva, CA Curcio - Progress in retinal and eye research, 2014 - Elsevier
Historically understudied, cholesterol in the retina is receiving more attention now because
of genetic studies showing that several cholesterol-related genes are risk factors for age …
of genetic studies showing that several cholesterol-related genes are risk factors for age …
Age-related macular degeneration (AMD): Alzheimer's disease in the eye?
K Kaarniranta, A Salminen… - Journal of …, 2011 - content.iospress.com
Age-related macular degeneration (AMD) is a late-onset, neurodegenerative retinal disease
that shares several clinical and pathological features with Alzheimer's disease (AD) …
that shares several clinical and pathological features with Alzheimer's disease (AD) …
Cell culture models of the ocular barriers
The presence of tight barriers, which regulate the environment of ocular tissues in the
anterior and posterior part of the eye, is essential for normal visual function. The …
anterior and posterior part of the eye, is essential for normal visual function. The …
Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins
The largest risk factor for age-related macular degeneration (ARMD) is advanced age. A
prominent age-related change in the human retina is the accumulation of histochemically …
prominent age-related change in the human retina is the accumulation of histochemically …
On phagocytes and macular degeneration
Age related macular degeneration (AMD) is a complex multifactorial disease caused by the
interplay of age and genetic and environmental risk factors. A common feature observed in …
interplay of age and genetic and environmental risk factors. A common feature observed in …