The global burden of neurological disorders is substantial and increasing, especially in low-
resource settings. The current increased global interest in brain health and its impact on …

Ten years ago, the proposition that healthcare is evolving from reactive disease care to care
that is predictive, preventive, personalized and participatory was regarded as highly …

Background: The recent COVID-19 pandemic swee** the globe has caused great concern
worldwide. Due to the limited evidence available on the dynamics of the virus and effective …

Chronic diseases (ie, noncommunicable diseases), mainly cardiovascular disease, cancer,
respiratory diseases and type-2-diabetes, are now the leading cause of death, disability and …

Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …

Genome‐scale metabolic models (GEM s) have proven useful as scaffolds for the integration
of omics data for understanding the genotype–phenotype relationship in a mechanistic …

Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

The term 'in silico clinical trials indicates the use of individualised computer simulation in the
development or regulatory evaluation of a medicinal product, medical device, or medical …

Chronic obstructive pulmonary disease (COPD) is a common, complex, and heterogeneous
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …

The exposome encompasses an individual's exposure to exogenous chemicals, as well as
endogenous chemicals that are produced or altered in response to external stressors. While …