Insights into the medicinal chemistry of heterocycles integrated with a pyrazolo [1, 5-a] pyrimidine scaffold
Pyrazolo [1, 5-a] pyrimidines are the dominant motif of many drugs; for instance, zaleplon
and indiplon are sedative agents and ocinaplon was identified as an anxiolytic agent. The …
and indiplon are sedative agents and ocinaplon was identified as an anxiolytic agent. The …
New advances in synthesis and clinical aspects of pyrazolo [3, 4-d] pyrimidine scaffolds
Abstract Pyrazolo [3, 4-d] pyrimidine ring system constitute an important class of heterocyclic
compounds which can serve as a promising scaffold exhibiting many pharmacological …
compounds which can serve as a promising scaffold exhibiting many pharmacological …
Synthesis and antiviral evaluation of some new pyrazole and fused pyrazolopyrimidine derivatives
AE Rashad, MI Hegab, RE Abdel-Megeid… - Bioorganic & medicinal …, 2008 - Elsevier
Some novel substituted pyrazole and pyrazolo [3, 4-d] pyrimidine derivatives 2, 4, 8, and 9
were synthesized. Also, some acyclic S-nucleosides of pyrazolo [3, 4-d] pyrimidine …
were synthesized. Also, some acyclic S-nucleosides of pyrazolo [3, 4-d] pyrimidine …
Analgesic, anti-pyretic and DNA cleavage studies of novel pyrimidine derivatives of coumarin moiety
RS Keri, KM Hosamani, RV Shingalapur… - European Journal of …, 2010 - Elsevier
A novel series of 4-[4-(6-phenyl-pyrimidin-4-yl)-phenoxymethyl]-chromen-2-ones [5–7 (a–e)]
were synthesized from various 4-bromomethyl coumarins 1 (a–e). The synthesized …
were synthesized from various 4-bromomethyl coumarins 1 (a–e). The synthesized …
O-4-Acetylamino-benzenesulfonylated pyrimidine derivatives: synthesis, SC-XRD, DFT analysis and electronic behaviour investigation
Abstract Beginning with 2-amino-6-methyl-pyrimidin-4-ol and 2, 6-diamino-pyrimidin-4-ol, 2-
amino-6-methylpyrimidin-4-yl 4-acetamidobenzenesulfonate (APABS) and 2, 6 …
amino-6-methylpyrimidin-4-yl 4-acetamidobenzenesulfonate (APABS) and 2, 6 …
Efficient Synthesis, SC-XRD, and Theoretical Studies of O-Benzenesulfonylated Pyrimidines: Role of Noncovalent Interaction Influence in Their Supramolecular …
Crystalline organic compounds, 2-amino-6-methylpyrimidin-4-yl benzenesulfonate (AMPBS)
and 2, 6-diaminopyrimidin-4-yl benzenesulfonate (DAPBS), were prepared via O …
and 2, 6-diaminopyrimidin-4-yl benzenesulfonate (DAPBS), were prepared via O …
[HTML][HTML] The curative activity of some arylidene dihydropyrimidine hydrazone against Tobacco mosaic virus infestation
A series of novel pyrimidine-based derivative compounds were synthesized and evaluated
for antiviral activity against Tobacco mosaic virus (TMV). All chemical structures of the …
for antiviral activity against Tobacco mosaic virus (TMV). All chemical structures of the …
Novel 2-amino-4-aryl-6-pyridopyrimidines and N-alkyl derivatives: Synthesis, characterization and investigation of anticancer, antibacterial activities and DNA/BSA …
A series of new 2-amino-4-aryl-6-pyridopyrimidines, and their N-alkyl bromide derivatives
were designed and synthesized by employing methyl substituted azachalcones. These …
were designed and synthesized by employing methyl substituted azachalcones. These …
A facile one pot synthesis of novel pyrimidine derivatives of 1, 5-benzodiazepines via domino reaction and their antibacterial evaluation
A new series of pyrimidine (8, 14, 18 and 23) embellished analogues of 1, 5-
benzodiazepines were synthesized by the one-pot domino approach using the catalyst …
benzodiazepines were synthesized by the one-pot domino approach using the catalyst …
Synthesis and Antimicrobial Activity of Some New Pyrazoles, Fused Pyrazolo[3,4-d]-pyrimidine and 1,2-Dihydroimidazo-[2,1-c][1,2,4]triazin-6-one Derivatives
SM Gomha, HME Hassaneen - Molecules, 2011 - mdpi.com
A novel series of 7, 7-diphenyl-1, 2-dihydroimidazo [2, 1-c][1, 2, 4] triazin-6 (7 H)-one 6a–h,
were easily prepared via reactions of novel 2-hydrazinyl-4, 4-diphenyl-1 H-imidazol-5 (4 H) …
were easily prepared via reactions of novel 2-hydrazinyl-4, 4-diphenyl-1 H-imidazol-5 (4 H) …