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2H/4H-Chromenes—A versatile biologically attractive Scaffold
2H/4H-chromene (2H/4H-ch) is an important class of heterocyclic compounds with versatile
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …
Targeted potent antimicrobial and antitumor oxygen-heterocyclic-based pyran analogues: Synthesis and computational studies
The process of creating a series of 3-amino-1-aryl-8-methoxy-1 H-benzo [f] chromene-2-
carbonitriles (4a-q) involved reacting 6-methoxynaphthalen-2-ol (1), the appropriate …
carbonitriles (4a-q) involved reacting 6-methoxynaphthalen-2-ol (1), the appropriate …
An insight into the synthesis and SAR of 2, 4-Thiazolidinediones (2, 4-TZD) as Multifunctional scaffold: A review
NS Sethi, DN Prasad, RK Singh - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
2, 4-Thiazolidinedione (2, 4-TZD) is a versatile pharmacophore, a privileged scaffold, and a
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …
Design, synthesis, antimicrobial activity and computational studies of novel azo linked substituted benzimidazole, benzoxazole and benzothiazole derivatives
Novel azo linked substituted benzimidazole, benzoxazole, and benzothiazole were
synthesized by diazo coupling and characterized by 1 H NMR, elemental analysis, FTIR and …
synthesized by diazo coupling and characterized by 1 H NMR, elemental analysis, FTIR and …
Determination of potential inhibitors based on isatin derivatives against SARS-CoV-2 main protease (mpro): a molecular docking, molecular dynamics and structure …
Abstract SARS-COV-2, the novel coronavirus and root of global pandemic COVID-19
caused a severe health threat throughout the world. Lack of specific treatments raised an …
caused a severe health threat throughout the world. Lack of specific treatments raised an …
Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P …
LM Al-Harbi, EA Al-Harbi, RM Okasha… - Journal of Enzyme …, 2023 - Taylor & Francis
A series of 1 H-benzo [f] chromene moieties (4a–z) were synthesised under Ultrasonic
irradiation and confirmed with spectral analyses. Derivative 4i solely possessed an X-ray …
irradiation and confirmed with spectral analyses. Derivative 4i solely possessed an X-ray …
Synthesis, characterization, anti-proliferative properties and DNA binding of benzochromene derivatives: Increased Bax/Bcl-2 ratio and caspase-dependent apoptosis …
MH Ahagh, G Dehghan, M Mehdipour… - Bioorganic …, 2019 - Elsevier
Amino-1-aryl-1H-benzo [f] chromene-2-carbonitrile derivatives were synthesized from three-
component reaction of arylaldehyde, malononitrile and 2-naphthol in the presence of 1, 4 …
component reaction of arylaldehyde, malononitrile and 2-naphthol in the presence of 1, 4 …
Antifungal and antibiofilm activities of chromones against nine Candida species
Candida species are the most common cause of fungal infections, and thus the emergence
of antifungal-resistant species and biofilm formation by Candida further threatens the limited …
of antifungal-resistant species and biofilm formation by Candida further threatens the limited …
Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo [h] chromene
Novel β-enaminonitrile/ester compounds (4, 6) and an imidate of 4 (9) were utilized as key
scaffolds for the synthesis of newly 2-substituted 4H-benzo [h] chromene (7, 8, 10, 11, 13 …
scaffolds for the synthesis of newly 2-substituted 4H-benzo [h] chromene (7, 8, 10, 11, 13 …
[HTML][HTML] Synthesis and Evaluation of Some New 4H-Pyran Derivatives as Antioxidant, Antibacterial and Anti-HCT-116 Cells of CRC, with Molecular Docking …
Colorectal cancer oncogenesis is linked to dysbiosis, oxidative stress and overexpression of
CDK2. The 4 H-pyran scaffold is considered an antitumoral, antibacterial and antioxidant …
CDK2. The 4 H-pyran scaffold is considered an antitumoral, antibacterial and antioxidant …