Microfold (M) cells are located in the epithelium covering mucosa-associated lymphoid
tissues, such as the Peyer's patches (PPs) of the small intestine. M cells actively transport …

M cells are specialized intestinal epithelial cells that provide the main machinery for
sampling luminal microbes for mucosal immune surveillance. M cells are usually found in …

Neuroepithelial crosstalk is critical for gut physiology. However, the mechanisms by which
sensory neurons communicate with epithelial cells to mediate gut barrier protection at …

As part of their life cycle, Gram-negative bacteria produce and release microvesicles (outer
membrane vesicles, OMVs) consisting of spherical protrusions of the outer membrane that …

Osteoprotegerin (OPG) is a circulating decoy receptor for RANKL, a multifunctional cytokine
essential for the differentiation of tissue-specific cells in bone and immune systems such as …

Immunoglobulin A (IgA) maintains a symbiotic equilibrium with intestinal microbes. IgA
induction in the gut-associated lymphoid tissues (GALTs) is dependent on microbial …

Zinc transporters play a critical role in spatiotemporal regulation of zinc homeostasis.
Although disruption of zinc homeostasis has been implicated in disorders such as intestinal …

Microfold cells (M-cells) are specialized cells of the intestine that sample luminal microbiota
and dietary antigens to educate the immune cells of the intestinal lymphoid follicles. The …

M cells are located in the follicle-associated epithelium (FAE) that covers Peyer's patches
(PPs) and are responsible for the uptake of intestinal antigens. The differentiation of M cells …

The follicle-associated epithelium (FAE) covering mucosa-associated lymphoid tissue is
distinct from the villous epithelium in cellular composition and functions. Interleukin-22 …