Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …

Matrix metalloproteinases (MMPs) play an important role in the degradation of extracellular
matrix components crucial for tumor growth, invasion and metastasis. MMPs are controlled …

An ultrasensitive photoelectrochemical sandwich immunoassay was developed to detect
matrix metalloproteinase-2 (MMP-2, antigen, Ag) based on CdS: Mn/CdTe cosensitized TiO2 …

Pancreatic cancer is a dismal disorder that is histologically characterized by a dense fibrotic
stroma around the tumor cells. As the extracellular matrix comprises the bulk of the stroma …

Background & Aims Pancreatic ductal adenocarcinoma (PDAC) metastasizes to liver at early
stages, making this disease highly lethal. Tissue inhibitor of metalloproteinases-1 (TIMP1) …

The global burden of colorectal cancer (CRC) is expected to increase, with 2.2 million new
cases and 1.1 million annual deaths by 2030. Therefore, the establishment of novel …

Colorectal cancer (CRC) is the third leading cause of cancer-related death in the western
world. In this study, we evaluated the expression of matrix metalloproteinase 2 gene (MMP2) …

Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal disease, usually diagnosed in an
advanced stage which gives a slight chance of recovery. Matrix metalloproteinases (MMPs) …

Colorectal cancer has a common cause of morbidity and mortality. Therefore, it is urgent to
detect reliable biomarkers to predict prognosis in CRC. Here, we determined the expression …

The growth, invasion and metastatic spread of cancer have been identified with the
deregulation of cell proliferation, altered intercellular and cell-substratum adhesion and …