Although classically thought of as a motor circuit, the cerebellum is now understood to
contribute to a wide variety of cognitive functions through its dense interconnections with the …

In motor neuroscience, state changes are hypothesized to time-lock neural assemblies
coordinating complex movements, but evidence for this remains slender. We tested whether …

Viral strategies are the leading methods for map** neural circuits. Viral vehicles combined
with genetic tools provide the possibility to visualize entire functional neural networks and …

Essential tremor (ET) is among the most prevalent movement disorders, but its origins are
elusive. The inferior olivary nucleus (ION) has been hypothesized as the prime generator of …

The inferior olive provides the climbing fibers to Purkinje cells in the cerebellar cortex, where
they elicit all-or-none complex spikes and control major forms of plasticity. Given their …

Inferior olivary activity causes both short-term and long-term changes in cerebellar output
underlying motor performance and motor learning. Many of its neurons engage in coherent …

The firing activity of ventral tegmental area (VTA) and substantia nigra pars compacta (SNc)
dopaminergic (DA) neurons is an important factor in sha** DA release and its role in …

The parallel closed‐loop topographic connections between subareas of the inferior olive
(IO), cerebellar cortex, and cerebellar nuclei (CN) define the fundamental modular …

Detailed single-neuron modeling is widely used to study neuronal functions. While cellular
and functional diversity across the mammalian cortex is vast, most of the available …

In-silico brain simulations are the de-facto tools computational neuroscientists use to
understand large-scale and complex brain-function dynamics. Current brain simulators do …