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Fluorescent nanoparticles for super-resolution imaging
Super-resolution imaging techniques that overcome the diffraction limit of light have gained
wide popularity for visualizing cellular structures with nanometric resolution. Following the …
wide popularity for visualizing cellular structures with nanometric resolution. Following the …
Understanding cell penetration of cyclic peptides
Approximately 75% of all disease-relevant human proteins, including those involved in
intracellular protein–protein interactions (PPIs), are undruggable with the current drug …
intracellular protein–protein interactions (PPIs), are undruggable with the current drug …
Cell penetrating peptides: classification, mechanisms, methods of study, and applications
A Gori, G Lodigiani, SG Colombarolli… - …, 2023 - Wiley Online Library
Cell‐penetrating peptides (CPPs) encompass a class of peptides that possess the
remarkable ability to cross cell membranes and deliver various types of cargoes, including …
remarkable ability to cross cell membranes and deliver various types of cargoes, including …
Application of semiconductor quantum dots in bioimaging and biosensing
In this review we present new concepts and recent progress in the application of
semiconductor quantum dots (QD) as labels in two important areas of biology, bioimaging …
semiconductor quantum dots (QD) as labels in two important areas of biology, bioimaging …
New modalities for challenging targets in drug discovery
E Valeur, SM Guéret, H Adihou… - Angewandte Chemie …, 2017 - Wiley Online Library
Our ever‐increasing understanding of biological systems is providing a range of exciting
novel biological targets, whose modulation may enable novel therapeutic options for many …
novel biological targets, whose modulation may enable novel therapeutic options for many …
[HTML][HTML] Membrane active peptides and their biophysical characterization
In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …
active peptides. These peptides exert their biological activity by interacting with the cell …
[HTML][HTML] Stapled peptides—a useful improvement for peptide-based drugs
Peptide-based drugs, despite being relegated as niche pharmaceuticals for years, are now
capturing more and more attention from the scientific community. The main problem for …
capturing more and more attention from the scientific community. The main problem for …
Emerging methods and design principles for cell‐penetrant peptides
Biomolecules such as antibodies, proteins, and peptides are important tools for chemical
biology and leads for drug development. They have been used to inhibit a variety of …
biology and leads for drug development. They have been used to inhibit a variety of …
Evaluation of the cytosolic uptake of HaloTag using a pH-sensitive dye
The efficient cytosolic delivery of proteins is critical for advancing novel therapeutic
strategies. Current delivery methods are severely limited by endosomal entrapment, and …
strategies. Current delivery methods are severely limited by endosomal entrapment, and …
Recent progress of food‐derived bioactive peptides: Extraction, purification, function, and encapsulation
Functional peptides constitute a class of small molecular peptide chains with specific
functions in biology and are typically composed of various amino acids. The chemical …
functions in biology and are typically composed of various amino acids. The chemical …